Figge J, Jabor A, Kazda A, Fencl V Anion gap
4) High lactic acid levels in combination with a high anion gap
are common features of mitochondrial disorders that are often overlooked.
One issue not addressed by the authors was the possibility that the 18-mmol/L anion gap
at presentation might be increased although remaining within the normal range.
Early diagnosis with early initiation of ethanol treatment is the modality of choice in units where haemodialysis is unavailable, and must be borne in mind in the patient with visual disturbance and high anion gap
At admission, the patient's chemistry laboratory results correlated with the diagnosis of anion gap
Physicians should be alert to the possibility of lactic acidosis in any metformin-treated patient with an unexplained anion gap
metabolic acidosis, regardless of risk factors and renal function.
Nevertheless, the clinical value of D-lactate measurement in metabolic acidosis, especially the contribution of D-lactate to the metabolic acidosis and high anion gap
in DKA, is not well appreciated.
The fourth step is to examine the serum electrolytes and anion gap
(AG) and to decide whether additional testing is required, e.
In children, a high anion gap
acidosis and fulminant hepatic failure, depression of the central nervous system, coma, renal failure and disseminated intravascular coagulation have been found (1).
The anion gap
(Na - (HCO3 + Cl) is normally less than 16 mEq/L.
1-5) We report a patient with small cell carcinoma of the lung with extensive liver metastases who had fatal high anion gap
metabolic acidosis secondary to lactic acid.
Ethylene glycol poisoning is associated with an increased osmolar gap and increased anion gap
metabolic acidosis (1).
The first step in evaluation of primary metabolic acidosis is to calculate the anion gap
= Na+ - (Cl- + HCO3-).
3] and finally the compound variables SIG, anion gap
(AG) and corrected anion gap
Q What is the normal range for anion gap
with the formula Na-(Cl+CO2)?