Volkhard Lindner, a vascular biologist at the University of Washington in Seattle, calls antisense "an interesting concept" for preventing arterial thickening after balloon angioplasty
But he cautions that Rosenberg's team has not proved that the antisense compound specifically blocks c-myb without interfering with other genes.
The c-myc gene is immediately activated by the injury to the vascular lining during angioplasty
and stent placement and peaks at 24 to 48 hours before subsiding.
It will be helpful for that small group of patients in whom balloon angioplasty
might otherwise fail, causing heart attacks or even death.
By contrast, pigs receiving hirudin at the two higher doses showed no evidence of clotting, a finding that suggests the experimental drug may one day ward off clots in people recovering from angioplasty
, Chesebro says.
7 millimeters (1/30 inch) in diameter, allowing it to be used in arteries too small to admit current balloon angioplasty
or stent delivery catheters.
Prior to the development of this total occlusion catheter, the only treatment alternatives for patients with total coronary occlusions not amenable to balloon angioplasty
were medication or bypass surgery.
Now new research, reported in the March 9 NEW ENGLAND JOURNAL OF MEDICINE, suggests that among heart attack patients already treated with clot-dissolving drugs, angiography and angioplasty
may be necessary only for those who experience recurrent heart pains (angina) either spontaneously or in response to a stress test given before hospital discharge.
Physicians deploy the Medtronic Interceptor Filter System through a groin incision, maneuvering it into place downstream from the graft before performing conventional balloon angioplasty
LAIS pioneered excimer laser angioplasty
and is the technological leader in the development of laser systems for cardiovascular applications.
Milner's team looked at 194 angioplasty
patients who were randomly assigned to treatment or control groups.
procedures, a balloon catheter is threaded through the femoral artery to the lesion and inflated, compressing the plaque associated with coronary artery disease against the vessel wall and restoring blood flow.
Such catheters are used in some 10 percent of all coronary angioplasty
A new study shows that heavy doses of fish-oil fatty acids may prolong the effectiveness of coronary angioplasty
, a procedure in which narrowed heart arteries are enlarged by insertion and inflation of a tiny balloon.
NYSE:MDT) today announced that it has received CE Mark clearance for the Sprinter(TM) Semi-Compliant Rapid Exchange Balloon Dilation Catheter for use in coronary angioplasty
CORDIS' SLEUTH ANGIOPLASTY
CATHETER GAINS MARKET APPROVAL