Results of the present study show that occupational exposures to benzene were associated with increased frequencies of aneuploid
sperm for chromosomes X, Y, or 21.
Consequently, breakages may result in viable gametes with aneuploid
numbers that can become stabilized through backcrossing or selfing.
Serotype AD strains of Cryptococcus neoformans are diploid or aneuploid
and are heterozygous at the mating-type locus.
The polyploid complex in the North American genus Claytonia (Portulacaceae) is structured around three basic numbers (x = 6, 7, and 8), each of which has given rise to separate polyploid lineages, interlineage polyploids, and aneuploids
clustering around the ploidy levels (White 1973; Grant 1981).
A model that explains the varying frequency of aneuploid
children with maternal age (J-shaped curve) as well as aneuploidy of paternal origin.
In addition, acoording to the recent committee opinion of American Society for Reproductive Medicine (ASRM) and the Society for Assisted Reproductive Technology (SART) the value of PGS for preimplantation screening of euploid and aneuploid
embryos are not conclusive, because the previuose studies have important limitations and more studies need to be perform in future (5).
Schoolcraft, "Association of abnormal ovarian reserve parameters with a higher incidence of aneuploid
blastocysts," Obstetrics and Gynecology, vol.
or polyploid karyotype was observed which displayed chromosome instability in the human lung adenocarcinoma cell line OM.
Subsequent studies from the same groups demonstrated proof of principle in plasma samples from pregnant women carrying aneuploid
fetuses (6, 7).
For patients who are low responders or who have a high number of aneuploid
embryos, our center does offer a "banking" package, where patients can do multiple CCS cycles at a discounted cost.
Higher frequency of muscle anomalies in aneuploid
is due to the delayed developmental processes in them.
(10,11) This dichotomous classification of DCIS lesions correlated well with a number of differences in many important tumor markers as well: in addition to the high-grade cytology of the cells of the comedo subtype, comedo DCIS lesions are also frequently negative for estrogen receptor (ER) expression, show frequent amplification of the HER2/neu gene, are frequently aneuploid
, have mutations in the suppressor gene p53, and high proliferative rates.
Nine specific proteins have been identified as candidate biomarkers, including lipocalin-1, which has demonstrated increased expression in aneuploid
blastocyst secretome, the material secreted from the embryo.
And a few times, they observed a single cell splitting into five daughter cells during a single division event, likely leading to aneuploid
Unlike a normal karyotype, an aneuploid
set of chromosomes is unstable.