Anaphylactoid purpura is diagnosed according to the European League against Rheumatism/Pediatric Rheumatology International Trials Organization/Pediatric Rheumatology European Society (EULAR/PRINTO/PRES) criteria.
Anaphylactoid purpura has been reportedly associated with bacterial and viral infections [3, 14].
Therefore, it is important to pay attention to the relationship between cellulitis, including streptococcal infection, and the development of anaphylactoid purpura. Regarding symptoms related to cellulitis-associated anaphylactoid purpura, only two patients, including our patient, presented with abdominal pain.
In the early 1800s, William Heberden, a physician in London, was the first to report anaphylactoid purpura, finding it in a 5-year-old boy with hematuria, abdominal pain, arthralgia and a skin rash (l).
Anaphylactoid purpura, also known as HSP, is an IgA-mediated vasculitis due to antigen-antibody complexes resulting from bacterial (Hemophilus influenza, parainfluenza, mycoplasma, Legionella, Yersinia, Shigella and Salmonella species) and viral (adenoviruses, Epstein-Barr virus, parvoviruses and varicella) infections, vaccinations (cholera, measles, paratyphoid A and B, typhoid, and yellow fever), medications (ampicillin, erythromycin, penicillin, quinidine, and quinine) or autoimmune disorders (2).
We conclude that the prompt diagnosis of anaphylactoid purpura followed by early multidisciplinary intervention constitutes appropriate management and prevents the emergence of complications and recurrence.