Incidence and severity of anaphylactoid
reactions to colloid volume substitutes.
Severity Included reactions Limited urticaria or pruritus Mild Limited cutaneous oedema Nasal flushing Conjunctivitis Diffuse urticaria Moderate Facial oedema Diffuse cutaneous erythema Bronchospasm without hypoxia Anaphylactoid
shock Bronchospasm with hypoxia Severe Laryngeal oedema with stridor or hypoxia Diffuse erythema with hypotension Diffuse or facial oedema with dyspnea TABLE 2: Characteristic of study patients.
It also has a very low risk of anaphylaxis or anaphylactoid
reaction as there is no dextran.
Management of anaphylactoid
reactions to intravenous N-acetylcysteine.
Immune immunoglobulin IgE-mediated anaphylactic or non-immune non-IgE anaphylactoid
reaction to amniotic fluid involve mast cell and basophil stimulation causing activation of complement, thrombin and coagulation cascade which are potentially fatal and require emergency management.
So, maltitol was suspected as the cause of the anaphylactoid
They can also cause anaphylactoid
reaction, cardiovascular effects, and aseptic meningitis .
purpura in children (Schonlein-Henoch syndrome): review with a follow-up of the renal complications," A.M.A.
Intravenous (IV) low-molecular-weight iron dextran has been associated with an incidence of anaphylaxis or anaphylactoid
reactions as high as 1.7% [10, 11].
In literature a 3-year-old child is reported to develop skin rashes and anaphylactoid
reaction with intramuscular ketamine administration.24 We are of the opinion that in our study, eritematous skin reactions, which regressed spontaneously in 26 patients (3.2%) in Group 1 were caused by fast injections and following acute increase in plasma histamine levels.
Allergic, hypersensitivity, anaphylactic and anaphylactoid
reactions are associated with this syndrome.
In one of these case reports, the patient had the complete spectrum of anaphylaxis but did not have a history of allergies or previous exposure of indigo carmine, and the authors suggested that indigo carmine directly may have triggered histamine release, consistent with an anaphylactoid
reaction associated with severe hypotension, bronchospasm, and urticaria .
The evidence given failed to identify a definitive cause of death but, delivering a narrative verdict, Ms Richards concluded it was most likely triggered by an anaphylactoid
(allergic) reaction to a drug.