Genotyping of human papillomavirus DNA in anal biopsies and anal swabs collected from HIV-seropositive men with anal dysplasia
. JAIDS Journal of Acquired Immune Deficiency Syndromes, 49(1), 32-39.
Association of anal dysplasia
and human papillomavirus with immunosuppression and HIV infection among homosexual men.
An alternative explanation is that because of the increase in screening programs for anal dysplasia
, anal cancers may be diagnosed more often than in the past.
Palefsky, a professor of medicine and the director of the Anal Dysplasia
Clinic at the UCSF Cancer Center.
HPV infection can result in diseases including internal and external genital warts and precancerous conditions, such as cervical and anal dysplasia
. Precancerous HPV-related conditions can progress into life-threatening diseases, including cervical, anal, and head and neck cancers.
Martin presented his own suggestions on whom, when, and how to screen for anal dysplasia
, using the [Pap smear].
Stressgen's heat shock protein fusion product, HspE7, designed to invoke a potent immune response, is in clinical development for a broad range of HPV-related diseases including cervical and anal dysplasia
, genital warts and recurrent respiratory papillomatosis (RRP).
Inovio Pharmaceuticals announced that it has commenced a Phase 2 clinical trial to evaluate the efficacy of VGX-3100 in adult men and women with human papilloma virus-related anal dysplasia
. Recruitment is ongoing for patients who are HIV-negative with histologically confirmed anal or perianal high-grade squamous intraepithelial lesions associated with HPV-16 and/or HPV-18.
So did almost 1 in 5 women, including 2 of 5 (40%) with anal warts and 5 of 8 (62%) with anal dysplasia
, compared with 20 of 122 (16%) with no anal lesions.