The anatomical distribution of NOP/ OFQ receptor ligand system has been observed in; cortex, amygdale
, hippocampus, pontine nuclei, central gray, lateral septum, anterior olfactory nucleus, raphe complex, locus coeruleus, substantia nigra, interpeduncular nucleus, and the spinal cord,  therefore, clearly suggesting that nociceptin plays significant roles in the stress responses.
Otherwise, the Behavioral Inhibition System (BIS), characterized by a decrease in HR and SCR, is constituted by a reticular neuronal structure including Amygdale
and the hippocampal septum system.
(2006) Enhancement of extinction memory consolidation: The role of the noradrenergic and GABAergic systems within the basolateral amygdale
. Neurobiology of Learning and Memory, 86, 123-132.
These complex circuits include the hippocampus, cerebral cortex, ventral, dorsal striatum, mPFC, VTA area and amygdale
Different studies showed increased expression of CRF-BP in the amygdale
, anterior pituitary and portal circulation follo wing increased CRF release (Van Den Eede et al., 2005).
There is considerably reduced nodal betweenness in the lingual gyrus and amygdale
in the IGD subjects.
There is research indicating that mindfulness practice could reduce emotional responses through adjusting the activity of the amygdale
.  The lateral prefrontal cortex takes part in the behavior control and emotional regulation through the feedback regulation of the amygdala.
The fine line between 'brave' and 'reckless': amygdale
reactivity and regulation predict recognition of risk.
The group found evidence of disturbances in the activity of the gene regulating the androgen receptor in the amygdale
of offspring, and noted changes in the receptors for a type of oestrogen and in the genes that regulate serotonin and GABA, signal substances in the brain known for their involvement in the regulation of anxious behaviour.
Inhibition of 11s-hydroxysteroid dehydrogenase, the foetoplacental barrier to maternal glucocorticoids, permanently programs amygdale
GR mRNA expression and anxiety-like behavior in the offspring.
2009), but extra-frontal brain regions, such as the amygdale
are also involved in impulsive control (Bechara 2005); our data are consistent with these earlier findings.
Automaticity and the amygdale
: nonconscious responses to emotional faces.
The soundness of the left amygdale
is considerably related to operation with positive and negative words at instant recollection, while at the same time the soundness of the right amygdala is not related to instant recollection operation with either valence (during the time that the left amygdala may back the encoding of both positive and negative components in addition to the strengthening of positive material, the right amygdala may chiefly back the fortification of negative material).