A comparison of
amrinone and glucagon therapy for cardiovascular depression associated with propranolol toxicity in a canine model.
Effects of dopamine, dobutamine,
amrinone and milrinone on regional blood flow in isoflurane anesthetized dogs.
In patients with PHT following mitral valve replacement,
amrinone produced a greater increase in cardiac index and RV ejection fraction than dobutamine (149).
The effects of
amrinone and glucagon on verapamilinduced cardiovascular toxicity in anaesthetized rats.
Amrinone lactate (Inocor) and milrinone (Primacor) also are being studied for treatment of NPE.
Amrinone is the prototype drug of the class, and numerous related compounds have been investigated.
Phosphodiesterase inhibitors (
amrinone and milrinone) are used to increase heart contractility in heart failure, as they stop the breakdown of cAMP and thus increasing their levels7.