On stipulated day the animals were slaughtered, their livers taken out and microsomes prepared for the estimation of activities of various membrane bound DME such as cytochrome P450 (CP), cytochrome b5 (CB), cytochrome-c-reductase (CCR), aniline hydroxylase (AH), acetanilide hydroxylase (AAH), benzphetamine demethylase (BD), aminopyrine
demethylase (APD), N.
2] breath analysis as a measurement of demethylation of stable isotope labeled aminopyrine
In order to evaluate activity of cytochrome P-450 an enzymatic assay was used which measures the formaldehyde produced by available Cytochrome P-450 when aminopyrine
is added as a substrate.
The composition of some herbal remedies used in various regions of the world is not regulated, and such remedies may contain contaminants such as mercury, aminopyrine
, theophylline and diazepam (Ernst, 1998).
Quantitative liver function in the elderly assessed by galactose elimination capacity, aminopyrine
demethylation and caffeine clearance.
Individuals who are taking various prescription drugs, such as warfarin, antipyrine, diazepam, aminopyrine
, and cimetidine would be interested in knowing that studies reported in the book indicate an arrested metabolism of medication when caffeine is used simultaneously.
was used as a substrate in this system.
6]-MedG) was decreased in rat liver when garlic powder was added to a diet containing aminopyrine
and sodium nitrite (96).
permits assessment of metabolic efficiency via analysis of the percentage of 14COZ in expired air .