Caption: Figure 4: Low-power examination shows plugs of granulation tissue in bronchioles, alveolar ducts
, and alveoli.
By contrast, Khajeh-Hosseini-Dalasm and Longest  suggested that total acinar deposition rates were insensitive to the gravity orientation when the geometry had more than three alveolar duct
Reaching a peak at days 4 to 5, hyaline membranes are composed of plasma proteins and cellular debris gathered into dense, glassy eosinophilic membranes found along alveolar septa with accentuation in alveolar ducts
. Inflammatory cells are relatively sparse unless a preexisting infectious pneumonia is the cause of DAD.
ResultsIn the control group, normal alveolar duct
, alveolar spaces and terminal bronchioles with regular size and shape of the alveoli were found (Figure-1).
(A, D, G, J, B, E, H, K Bright-field light microscopy of representative sections of lung from control mice (A, D, G, J) and Ti[O.sub.2]-NB-exposed mice (B, E, H, K); sections from Ti[O.sub.2]-NB-exposed mice show inflammatory lesions primarily localized to alveolar duct
Additionally, there is evidence of bronchiolar metaplasia of the alveolar ducts
(Pinkerton et al.
Hyperinflation and linear markings are radiologic evidence of bronchiolar, peribronchiolar, and/or alveolar duct
inflammation (Calderon-Garciduenas et al.
Septum of alveolar duct
or alveolus Including septa of alveolar outpocketings of respiratory bronchioles in humans 9.
Some cases of organizing DAD may, however, contain comparatively prominent intraalveolar or alveolar duct
fibrosis and therefore, OP may arise in the histologic differential diagnosis.
The following histologic features were evaluated using a semiquantitative scale: macules, defined as collections of dust-laden macrophages in a size range of 0.1-0.6 mm within the walls of respiratory bronchioles and adjacent alveoli; nodules, defined as fibrotic lesions up to 1 cm in size with round, irregular, or serpiginous borders and containing dust-laden macrophages; and interstitial fibrosis, defined as diffuse or irregular fibrosis of alveolar septa and/or alveolar ducts
Histopathology.--Morphologically, the lesions of LAM are distinctive and, under most circumstances, are not easily confused with normal anatomic structures (like alveolar duct
smooth muscle hyperplasia).
(1977) did not mention the existence of alveolar ducts
in Platanista sp.
In diffuse lung adenocarcinoma, cancer cells usually grow invasively along alveolar and alveolar ducts
, spread along the lymphatic vessels, or metastasis to bilateral lungs by the way of lymph and blood.[sup], As a result, diffuse pulmonary adenocarcinoma in the X-ray manifests pulmonary diffuse nodular or patchy shadow.
Lung parenchyma showed marked congestion and thickening of the alveolar septa by fibrosis (Figure 1) accompanied by loose plugs of proliferating fibroblasts within the alveolar ducts
and airspaces (Figures 2-4).
Organizing pneumonia (OP) is characterized by plugs of collagen and fibroblasts that fill respiratory bronchioles, alveolar ducts
and alveoli (Figure 3).