Amongst the maternal risk factors, the most common risk factors associated with fetal stroke are alloimmune thrombocytopenia
and trauma (2) .Other maternal conditions are coagulation disorders, seizure disorders, viral or bacterial infection, febrile illness, amniocentesis, medications like warfarin, drug abuse (Cocaine),cholestasis, pancreatitis.
A prenatal diagnosis of neonatal alloimmune thrombocytopenia
would have allowed for treatment with gamma globulin, which could have avoided the intracranial hemorrhage.
The ASH defined ITP as  isolated thrombocytopenia with no clinically apparent associated conditions or other causes of thrombocytopenia (e.g., HIV infection, systemic lupus erythematosus, lymphoproliferative disorders, myelodysplasia, agammaglobulinemia or hypogammaglobulinemia, drug-induced thrombocytopenia, alloimmune thrombocytopenia
, congenital hereditary nonimmune thrombocytopenia) .
Immune thrombocytopenia, neonatal alloimmune thrombocytopenia
, and post-transfusion purpura.
She had already lost two baby boys because she has neo-natal alloimmune thrombocytopenia
- a condition where her antibodies attack platelets in the foetus's blood stopping it clotting.
Catherine had lost two boys in the womb because of her condition, neo-natal alloimmune thrombocytopenia
Catherine, 30, had already lost two baby boys in the womb because of the same condition called neo-natal alloimmune thrombocytopenia
Catherine and husband Ian, 27, had decided to give up on parenthood, but a TV documentary about the condition - neo-natal alloimmune thrombocytopenia
- changed their minds.