can be cell mediated or antibody mediated.
Those T cells could lead to allograft rejection
or graft-versus-host disease if left unchecked in allogeneic transplantation.
These complications are not observed in the enteric drainage technique of pancreas transplantation; (15) however, the main disadvantage of enteric drainage technique is lack of a noninvasive access for detection of pancreas allograft rejection
In transplantation models, the Th1 cytokine profile often associates with allograft rejection
, while the Th2 profile favors the acquisition of tolerance and stable graft survival .
20] reported a 42% acute renal allograft rejection
rate but only 2/5 cases were proven by biopsy.
The impact of corneal allograft rejection
on the long-term outcome of corneal transplantation.
Thus, KIM-1 may be involved in the renal allograft rejection
The diagnosis of allograft rejection
on ultrasound is often an elusive one and may be deferred to the clinical history as well as a percutaneous biopsy.
However, before planning clinical trials in recipients, the start of such a novel therapeutic strategy to prevent allograft rejection
could consist of designing and performing a quadruple drug treatment of deceased (brain-dead) donors aimed at generating donor-derived tolerogenic dendritic cells.
These first clinical observations support the potential of stem cells as a novel cell therapy to prevent allograft rejection
and interstitial fibrosis/tubular atrophy.
Multicenter randomized trial comparing tacrolimus(FK506) and cyclosporine in the prevention of renal allograft rejection
Herpes simplex vims keratitis: histopathologic inflammation and corneal allograft rejection
For example, ECP has been used in the treatment of patients following acute allograft rejection
in cardiac, lung, renal or liver transplantation, acute and chronic graft-versus-host disease (GvHD), systemic lupus erythematosus (SLE), systemic scleroderma (SSc), rheumatoid arthritis (RA) and pemphigus vulgaris (PV).
1,2) Acute tubular necrosis, acute and chronic allograft rejection
and immunosuppressive medications-induced nephropathy are among the medical complications.
The standard of care in adolescents should be similar to that in adults, including surveillance EMB for heart allograft rejection
for 6 to 12 months after HT.