Those T cells could lead to allograft rejection or graft-versus-host disease if left unchecked in allogeneic transplantation
If high risk patients have HLA compatible sibling donor, allogeneic transplantation
should be performed (24).
to continue examining and collecting global data on the practices, safety, quality, efficacy and epidemiology of allogeneic transplantation
and on ethical issues, including living donation, in order to update the Guiding Principles on Human Organ Transplantation;
Quantitative analysis of cytomegalovirus (CMV) viremia using the pp65 antigenemia assay and the COBAS AMPLICOR CMV MONITOR PCR test after blood and marrow allogeneic transplantation
Umbilical cord blood as a hematopoietic source of stem cells has generated a great deal of scientific, clinical, and public interest of late, emerging as an attractive source of stem cells for allogeneic transplantation
effort to establish a publicly accessible bank for allogeneic transplantation
and has collected more than 7,000 placental blood specimens.
Long-term follow-up after reduced-intensity conditioning allogeneic transplantation
for acute myeloid leukemia/myelodysplastic syndrome: Late CNS relapses despite graft-versus-host disease.
BL-8040 also mobilizes stem cells from the bone marrow to the peripheral blood, enabling their collection for subsequent autologous or allogeneic transplantation
in cancer patients.
is most frequently performed in children with high-risk and relapsed leukemias, myelodysplastic syndromes, aplastic anemia, congenital BM failure syndromes, beta thalassemia major, and various congenital metabolism disorders (1), (7-11).
This work should shed new light on understanding the immunology of HSCs and other stem cells and may lead to development of novel strategies for successful allogeneic transplantation
of human patients," Zhang said.
Non-myeloablative allogeneic transplantation
(NMAT) can provide prolonged remissions in patients with advanced B-cell lymphoma via the graft versus lymphoma effect, though patients and donors need to be carefully selected.
In an accompanying editorial, Elaine Glukman, MD of the Hopital Saint-Louis in France said that cord blood has several advantages over adult marrow for allogeneic transplantation
of hematopoietic stem cells.