allele


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  • noun

Synonyms for allele

(genetics) either of a pair (or series) of alternative forms of a gene that can occupy the same locus on a particular chromosome and that control the same character

References in periodicals archive ?
Since its release, mNeonGreen has been available exclusively at Allele biotechnology, under a novel licensing model created by Allele specifically for academic users (Nature Methods: Technology Feature).
FOXO3 controls the expression of multiple genes regulating cell survival, autophagy, cell proliferation and metabolism which ultimately results in stress resistance, nutrient sensing and tumor suppression in various cells and tissues.5 FOXO3 also plays an essential role in preventing various age-related diseases such as type 2 diabetes mellitus, cardiovascular diseases, neurodegenerative disorders and cancers.3 Various single nucleotide polymorphisms (SNPs) of FOXO3 gene have been observed to be associated with multiple age-related diseases and longevity.6 Among these SNPs, the minor allele "A" of rs2802288 is particularly found to be associated with longevity and healthy aging in individuals.7,8 The far reaching effects of FOXO3 warrant detailed study of this gene.
Allele frequency is to display gene diversity in one population of one species.
Fetuin-A is encoded by the AHSG gene located at the chromosome 3q27, composed of seven exons and spanning 8.2 kb of deoxyribonucleic acid (DNA).7 The gene has multiple variants but the specific allele of interest for this study is rs4918.
Because of the low genetic diversity at Glu-D3, no allele specific markers were developed (Liu et al., 2010), and the effect of Glu-D3 on bread making quality is also negligible as compared to other Glu-3 loci (Gupta et al., 1989; Zhang et al., 2012).
In addition, the etiologic fraction (EF) was calculated to determine how much each allele, genotype, or haplotype contributed to susceptibility to CR.
The association between the occurrence of carbamazepine-induced cADRs and the HLA allele among the Thai population has been reported previously in only one study.
Conclusions: Data demonstrates that frequency and distribution of mutant T allele was more prevalent as compared to wild type A allele in the study group.
We used the DNA Isolation Kit for Blood/Bone Marrow/Tissue (Roche Molecular Diagnostics, Meylan, France) to extract DNA, and the specific single-stranded oligonucleotide probe (SSO) technique with the Dynal RELI SSO (Invitrogen, Wirral, United Kingdom) HLA-DRB typing kit for allele typification in all samples.
Allele has developed proprietary techniques to generate iPSCs and to derive high quality tissue-specific cells with much less technical difficulties than other known methods.
Allele has developed proprietary techniques to generate iPSCs and to derive high quality tissue specific cells with much less technical difficulties than other known methods.
In CD patients, the mutant allele (T) and genotype (AT+TT) of FUT2 A385T were less prevalent in patients with ileocolonic CD than in colonic CD (41.67% versus 59.41%, P = 0.001, OR = 0.488, and 95% CI = 0.324-0.734; 63.33% versus 83.17%, P = 0.002, OR = 0.350, and 95% CI = 0.178-0.686, resp.) (Table 4).
We included any study that met all of the following criteria: (1) the study was a cross-sectional, case control, or cohort design; (2) clear diagnostic criteria for CAD were established; (3) the association between of HPA-2a/b, GP VI T13254C, and GP Ib[alpha] VNTR with risk of CHD was investigated; and (4) the odds ratios (ORs)/risk ratio (RR, for cohort studies) and the corresponding 95% confidence intervals (CIs), or the distributions of genotype and allele frequency were reported.
In the case that an allele could not be fully phased using the default set of 4000 read-pairs, the number of read-pairs was increased to 16000.
In this study, with the support of clinical data, we were able to investigate the HLA - DRB1 allele frequencies in NPC patients and healthy controls, as well as in several clinical and pathological subgroups of NPC in Han and Uyghur subjects.