Re-induction of complete remission with a new synthetic retinoid, Am-80, for relapse of acute promyelocytic leukaemia previously treated with all-trans
We found evidence for strong intramolecular band structure , but this does not provide a clear indication of the type of dipole ordering along the surface normal: both an all-trans
and some type of alternating trans-gauche conformations are possible from the experimental band mapping data.
Structural differences between adapalene, a synthetic retinoid, and all-trans
retinoic acid, the natural compound, give the two agents strikingly different properties, Dr.
Larvae expressing Channel-rhodopsin-2 (ChR2) in class IV neurons were fed with all-trans
retinal, which is essential for the synthesis of ChR2 (Nagel et al, 2003).
We are optimistic about tamibarotene's prospects in advanced NSCLC based on clinical data indicating a statistically significant improvement in these patients when all-trans
retinoic acid (ATRA) was combined with paclitaxel and cisplatin," said Daniel Levitt, MD, Ph.
Kappa will market its novel, all-trans
vitamin K product under the trade name K2VITAL.
Biological activity of all-trans
retinol requires metabolic conversion to all-trans
retinoic acid and is mediated through activation of nuclear retinoid receptors in human keratinocytes.
conformation in the methylene sequence is adopted in the intrasheet and the nature of the intersheet shear is mainly controlled by Van der Waals interactions.
retinoic acid (RA), a metabolite of vitamin A, acting through a plasma membrane retinoic acid-binding protein, has been shown to reduce electrical coupling between horizontal cells both in situ and between cell pairs in culture (10).
Tamibarotene is an orally available, rationally designed, synthetic retinoid compound designed to potentially avoid toxic side effects by binding to its molecular target more selectively than all-trans
retinoic acid (ATRA), the current first-line treatment for APL.
On the back of Superman we can fly back in time to the publication of the results of the Alpha-Tocopherol Beta-Carotene (ATBC) Cancer Prevention Study (which indicated that supplementation of all-trans
(synthetic)-BC to long-term "well-nourished" Finnish smokers may actually increase the risk of lung cancer or decrease that of prostate cancer; N Engl J Med, 1994) and hear the cacophony.
This metastable polymorph is termed also planar zig-zag or all-trans
A representative HPLC chromatogram of one such hexane extract of larvae shows the presence of the biological all-trans
MF, identified by comparing its retention time with that of the external standard (data not shown) and that of the internal standard [ILLUSTRATION FOR FIGURE 1 OMITTED].
The FDA has granted Orphan Drug Designation for APL and Fast Track Designation for the treatment of adult patients with relapsed or refractory APL following treatment with all-trans
retinoic acid (ATRA) and arsenic trioxide.
The doses were calculated based on the volunteer's body weight and on the all-trans
lutein content of each formulation, so that the same amount of all-trans
lutein was delivered in each formulation.