Materials and methods: Between May 2006 and July 2006, 60 female Wistar Albino rats aged three months were randomly allocated to three groups: sham operated receiving no treatment (Shm); ovariectomized-alendronate receiving 1 mg/kg/day alendronate sodium
(Ovx-A), and ovariectomized-vehicle receiving 1 mL/kg/day physiological saline (Ovx-PS).
By various mechanisms of action, alendronate sodium
can enhance bone strength, alleviate and prevent osteoporosis, effectively reduce the risk of fracture in centrum, hip bone and other parts.
Perkins, "In vitro disintegration studies of weekly generic alendronate sodium
tablets (70 mg) available in the US," Current Medical Research and Opinion, vol.
Doctors recommend taking Fosamax (alendronate sodium
) with a full glass of water at least 30 minutes before eating a meal--and remaining in an upright position for at least 30 minutes after taking the drug--to avoid heartburn, a side effect of the drug.
. Prevention and treatment postmenopausal women, treatment in men.
In September, 2000, the FDA approved alendronate sodium
as a treatment to increase bone mass in men with osteoporosis.
Data from a McMaster University, Toronto, Ontario, endoscopy study published recently in Gastroenterology and presented at the annual meeting of the American Society for Bone and Mineral Research (ASBMR) showed that risedronate sodium (Actonel) reduced the incidence of gastric ulcers in healthy, postmenopausal women relative to another osteoporosis therapy, alendronate sodium
. Research demonstrated that gastric ulcers developed in three times as many participants treated with alendronate as those treated with risedronate.
 showed that alendronate sodium
significantly decreased intima-media thickness in the carotid artery during a one-year follow-up.
According to the agreement and a shared sales force agreement with Mission, in addition to promoting Dara's products Soltamox (tamoxifen citrate), Gelclair and Bionect, the Alamo sales team will also carry three Mission Pharmacal products: Ferralet 90 (for anemia), BINOSTO (alendronate sodium
effervescent tablet indicated for the treatment of osteoporosis), and Aquoral (for chemotherapy/radiation therapy-induced dry mouth).
Clinical studies show that Fosamax (alendronate sodium
) increases bone mass in the spine and hip and lowers the rate of bone breakdown.
Fosamax (alendronate sodium
) helps build bone in the spine and hip and lowers the rate of bone breakdown, reducing the risk of broken bones in people with osteoporosis.
Merck case, rejecting the claims of a plaintiff who blamed her dental and jaw-related problems on her FOSAMAX (alendronate sodium