alendronate


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Related to alendronate: Fosamax, alendronate sodium
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Synonyms for alendronate

a tablet (trade name Fosamax) prescribed to prevent or treat osteoporosis in women after menopause

References in periodicals archive ?
Materials and methods: Between May 2006 and July 2006, 60 female Wistar Albino rats aged three months were randomly allocated to three groups: sham operated receiving no treatment (Shm); ovariectomized-alendronate receiving 1 mg/kg/day alendronate sodium (Ovx-A), and ovariectomized-vehicle receiving 1 mL/kg/day physiological saline (Ovx-PS).
Exclusion criteria included patients exhibiting metastasis at L1-L3, Chronic renal failure, Metabolic bone disease, other malignancies of prostate, Contraindications of the Alendronate i.
By various mechanisms of action, alendronate sodium can enhance bone strength, alleviate and prevent osteoporosis, effectively reduce the risk of fracture in centrum, hip bone and other parts.
The researchers received no outside funding, though their findings were derived from an analysis of the placebo group of the FLEX trial, a manufacturer-sponsored study comparing extended alendronate sodium treatment with placebo in a large cohort of women treated 5 years on alendronate (JAMA 2006;296:292738.
Effect of alendronate for reducing fracture by FRAX score and femoral neck bone mineral density: the Fracture Intervention Trial.
The aminobisphosphonate alendronate is primarily used for the treatment of osteoporosis in postmenopausal women and elderly men.
5 received 70 mg oral Alendronate weekly, testosterone, 1gr elemental calcium and 400 U vitamin D daily.
Alendronate, also known by the brand name Fosamax, is commonly taken by women with osteoporosis to reduce the risk of fracture.
The research team incorporated alendronate into the hyhrid molecules because once in the bloodstream, it goes directly to the hone surface, where it slows the rate of bone breakdown.
5 mg/day of prednisone (or the equivalent) to treatment with alendronate 5 mg/day or 10 mg/day or placebo.
5) Prolonged use of alendronate over 7 to 10 years has shown a continued increase in the bone mineral density without any adverse skeletal events.
Routine BMD measurement "1-2 years after stopping prolonged alendronate therapy may not be useful for predicting the patient's fracture risk," said Dr.
Summary: EffRx Pharmaceuticals announced that the first European filing for marketing approval of EX101, a once-a-week 70mg buffered effervescent alendronate, for the treatment of osteoporosis, has been submitted.
21 September 2010 - Swiss drug delivery company EffRx Pharmaceuticals SA and Nycomed said today that the first European filing for marketing approval of EX101, a once-a-week 70mg buffered effervescent alendronate, for the treatment of osteoporosis, has been submitted.