pancreatitis

Stellate cell activation in alcoholic pancreatitis. Pancreas, 27(4):316-20, 2003.

In Japan, a questionnaire to assess alcohol use among patients with alcoholic pancreatitis found that women developed pancreatitis at a younger age, with shorter duration of alcohol use, and after smaller cumulative amounts of alcohol consumption compared with male patients (Masamune et al.

Corresponding HRs were 7.9 (5.1-12) for any alcoholic liver disease, 4.1 (1.7-10) for alcoholic pancreatitis, and 3.4 (1.9-6.1) for any pancreatitis.

Researchers discovered that there was a common DNA variant on the X chromosome that is present in 26 percent of men without pancreatitis, but jumps to nearly 50 percent of men diagnosed with alcoholic pancreatitis.

Gender and genetic and other co-factors may play pivotal roles, and the term 'alcoholic pancreatitis' therefore does not necessarily imply chronic alcoholism or harmful patterns of alcohol use.

Subsequently, a frequent association with chronic alcoholic pancreatitis was reported.

Despite its important aetiologic role, the pathophysiology of alcoholic pancreatitis is not fully understood.

Although it has long been thought that alcoholic pancreatitis is a chronic disease from the outset, evidence is accumulating to indicate that chronic damage in the pancreas may result from repeated attacks of acute tissue inflammation and death (i.e., necroinflammation).

This explains why coffee consumption can reduce the risk of alcoholic pancreatitis."

The researchers, led by Prof Michael Goldacre, said the increase partly reflected an increase in alcoholic pancreatitis due to growing use of alcohol, particularly among young people.

"The doctor's death certificate indicates the cause of death was acute alcoholic pancreatitis.

When caring for patients with alcoholic pancreatitis be especially alert for signs of alcohol withdrawal such as tachycardia, restlessness, agitation, tremors, anxiety, and diaphoresis.

It was reported that patients with acute alcoholic pancreatitis had serum concentrations of amylase lower than those with non-alcoholic pancreatitis, but the serum lipase concentrations were similar in the both forms of the disease.

No alcoholic pancreatitis was found in SAP in 2016, which was only 6.7% in 2011.

Patients with mild AP considered in terms of Glasgow prognostic score of less than three, and pain assessment of less than four On Visual Analogue Scale (VAS), post-Endoscopic Retrograde Cholangiopancreatography (ERCP) AP, history of Cholelithiasis and not requiring emergency admission, post blunt trauma pancreatitis and patients of alcoholic pancreatitis were included.