In a study conducted in America, to establish the variability in the upper limit of normal (ULN) for alanine aminotransferase
(ALT) across different laboratories, it was found that there is wide variability in ALT ULN across different laboratories11.
5 g/L for 28 days on the activities (MeanSD) of glutamate dehydrodegase (GDH M formozan/mg protein/h) aspartate aminotransferase (ASAT M oxaloacetate/mg protein/h) and alanine aminotransferase
(ALAT M pyruvate/mg protein/h) of gill muscles and liver of a freshwater fish Cyprinus carpio.
in detecting liver damage is more important than the others because level of this enzyme in the cytoplasm of hepatic cells is several times higher than the serum's level of that and when the membrane was damaged, the enzyme was removed from the cells and its serumic concentration increases.
HCV carriers with normal alanine aminotransferase
levels: healthy persons or severely ill patients?
The values of serum alanine aminotransferase
(ALT) and aspartate aminotransferase (AST), activator protein-1 m-RNA, [alpha]-smooth muscle actin, transforming growth factor-[beta], 14-hydroxynonenal and 8-oxo20deoxyguanosine, all markers of oxidative stress, liver compromise and stellate cell activation were significantly lower in the treatment group than the non treatment group.
Primary outcome parameter was the rate of alanine aminotransferase
(ALT) normalisation after 12 weeks.
A healthy alanine aminotransferase
level is 10 to 40 U/L.
About a quarter of both groups had elevated alanine aminotransferase
(ALT) levels at baseline.
ORLANDO -- Consider a diagnosis other than nonalcoholic fatty liver disease when an obese child or adolescent presents with elevated levels of the liver enzyme alanine aminotransferase
ORLANDO -- Consider a diagnosis other than nonalcoholic fatty fiver disease when an obese child or adolescent presents with elevated levels of the fiver enzyme alanine aminotransferase
, a retrospective study suggests.
This drug was indicated because anatomopathological findings showed intense periportal inflammation (grade 4) and increased alanine aminotransferase
(ALT) levels (195 U/L).
First was the blood test which would measure levels of two enzymes - alanine aminotransferase
(ALT) and gamma-glutamyl transferase (GGT) - which the liver produces when it is not working properly.
By day 4 of hospitalization, the patient's level of creatine phosphokinase had elevated to 146 266 U/L, the level of aspartate aminotransferase was 3082 U/L, the level of alanine aminotransferase
was 1144 U/L, and the level of lactate dehydrogenase was 4687 U/L.
The drug has proven an effective inhibitor of virus replication and has indicated improvements in the increase of alanine aminotransferase
(ALT) and overall liver health.
Other endpoints observed in the study were a 57 percent increase in liver glycogen and no changes in muscle glycogen or in levels of plasma insulin or alanine aminotransferase