akinesis


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Related to akinesis: dyskinesis
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Synonyms for akinesis

motionlessness attributable to a temporary paralysis

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Takotsubo cardiomyopathy is a condition characterized by a sudden onset of cardiac symptoms along with transient left ventricular apical wall akinesis and ballooning, electrocardiography (EKG) changes with ST elevation or depression, formation of abnormal Q-wave, and/ or elevation of cardiac enzymes in the absence of coronary artery disease.
There was akinesis of the inferior wall and significant hypokinesis of the anterolateral wall.
Echocardiograms then and subsequently have shown a left ventricular ejection fraction of 20% with inferoposterior akinesis, a restrictive filling pattern consistent with elevated left atrial and left ventricular end-diastolic pressures, severe mitral and tricuspid regurgitation, and a pulmonary arterial systolic pressure of 70 mm Hg.
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On the ventriculography the left ventricular sizes were normal, akinesis at the anterior and apical portion of the left ventricle, mild mitral regurgitation were seen.
A subsequent bedside transthoracic echocardiogram (TTE) showed severe segmental left ventricular systolic dysfunction with akinesis of the middle and distal segments of the left ventricle and hypokinesis of the mid and distal inferior walls.
These include left ventricular dysfunction with akinesis or hypokinesis due to ischemia, infarction or cardiomyopathy, left ventricular aneurysm, atrial or ventricular septal defects, and patent foramen ovale (PFO).
Perfusion Rest/Stress Test Results Gated Wall Motion Study Results Abnormal Wall Motion (Hypokinesis or Akinesis, n = 116) Fixed defects; n = 22 19 (86%) Reversible defects; n = 129 68 (53%) Fixed and reversible defects; n = 30 29 (97%) Normal perfusion; n = 110 0 Perfusion Rest/Stress Test Results Normal Wall Motion (n = 171) Fixed defects; n = 22 2 (9%) Reversible defects; n = 129 59 (46%) Fixed and reversible defects; n = 30 1 (3%) Normal perfusion; n = 110 109 (99%) Perfusion Rest/Stress Test Results Nongated(*) (n = 4) Fixed defects; n = 22 1 (5%) Reversible defects; n = 129 2 (1%) Fixed and reversible defects; n = 30 0 Normal perfusion; n = 110 1 (1%)
This cine display of the heart in near real time allows the observer to identify areas of hypokinesis, akinesis, and dyskinesis.
The patients were at least 18 years of age with LV wall motion abnormalities (anteroapical akinesis or dyskinesis) secondary to MI, an LV ejection fraction (EF) between 15% and 40% determined by the echocardiography and measured by echocardiography core laboratory (core lab).
The characteristic echocardiogram finding in Takotsubo cardiomyopathy is transient apical ballooning with akinesis or hypokinesis in the apical and/or mid ventricular regions (typical variant) or isolated midventricular hypokinesis (apical sparing variant).
The cardiac biomarkers were elevated (12 ng/mL for troponin and 123 IU/L for creatine kinase-MB), and echocardiography found an inferior akinesis with an ejection fraction of 45%.
CMRI short axis (SAX) (Figure 1), two-chamber (2CH) (Figure 2), three-chamber (3CH) (Figure 3), and four-chamber (4CH) (Figure 4) CINE imaging confirm global mild hypokinesis with proximal apical-inferior wall thinning and akinesis, and mid- and basilar-inferior septum, inferior wall, and posterior-lateral wall myocardial thinning with mild hypokinesis.
Left ventriculography showed a severely depressed ejection fraction and akinesis of the anterior and anterolateral walls.
Cardiac catheterization revealed marked akinesis of the mid and apical left ventricle with hyperkinesis of the basal segments (Figs.