agonist


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Related to agonist: Agonist muscle, Dopamine agonist
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Synonyms for agonist

the principal character in a work of fiction

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someone involved in a contest or battle (as in an agon)

a muscle that contracts while another relaxes

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(biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reaction

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References in periodicals archive ?
- French clinical stage biotech company Enyo Pharma has completed its phase Ib clinical trial evaluating the safety, pharmacokinetics and pharmacodynamics of its FXR agonist compound EYP001 in patients with chronic hepatitis B virus infection, the company said.
Normalization of expression from individual promoters to total expression also highlights the differential transcriptional response to each agonist (Figure S1).
Since the possible standardization for GnRH agonist trigger criteria that will yield optimal outcomes have not yet been established, some authors used increased estradiol levels as a criterion (20), whereas others assessed only excess number of available follicles during the late follicular phase of ovarian stimulation (21).
In the present study, we sought to evaluate the short-term effects of TLR2, TLR3, TLR4, and TLR9 agonists on Fc[gamma]R-mediated phagocytosis, as well as the participation of LTs in this interaction.
The drug will also be the first dual TLR7and 8 agonist administered directly into a tumor in a clinical setting.
Using RT-PCR, we analyzed the Nurr1 mRNA level in PBMC from 362 sporadic PD patients and 193 HCs from Southern China, and found that the Nurr1 expression level in de novo subgroup with a tendency of nonsignificant decrease compared to HCs, but a statistically significant increase in both DA agonist or DA agonist and L-dopa subgroups, which indicated that DA agonists may exert an up-regulation effect on the expression of Nurr1 in PBMC.
Each participant was randomly allocated to either GnRH antagonist protocol during early and late follicular phase group or GnRH antagonist protocol (flexible) group or long GnRH agonist protocol group.
"Our additional analyses adjusting for injecting drug use in the past month suggest that maintenance opioid agonist therapy reduces the incidence of HCV infection in part by decreasing the frequency of injection, which will also lower the risk for acquiring HIV and other blood-borne pathogens," wrote Dr.
The Study: The readmission rate of 31,658 children two-to-eighteen years old hospitalized for asthma between 2005-2007 were stratified based on the refill rate of the three medicines the children were prescribed: beta agonists, oral steroids and inhaled steroids.
NORDIC BUSINESS REPORT-September 12, 2013-Karo Bio awarded USD0.5m in funding from the National MS Society to develop ERbeta agonists treatment for progressive MS(C)2013 M2 COMMUNICATIONS http://www.m2.com
Aminophylline increases the toxicity but not the efficacy of an inhaled beta-adrenergic agonist in the treatment of acute exacerbations of asthma.
Participants in the study underwent a standard set of blood tests taken immediately before their injection of LHRH agonist. All patients had been on therapy for at least 3 months before entering the study and all complied with the schedule for treatment.
To confirm superiority of insulin degludec/liraglutide versus unchanged glucagon-like peptide-1 (GLP-1) receptor agonist therapy in controlling glycaemia in insulin naive subjects with type 2 diabetes mellitus (T2DM) inadequately controlled on GLP-1 receptor agonist therapy in combination with metformin.