Vitamin D-binding protein levels in plasma and gingival crevicular fluid of patients with generalized
aggressive periodontitis. Int J Endocrinol.
Platelet activation and platelet-leukocyte interaction in generalized
aggressive periodontitis. J Leukoc Biol 2016;100:1155-66.
The second major feature of PLS is severe periodontitis, which starts at the age of 3 or 4 years.1,4
Aggressive periodontitis begins with the primary dentition leading to premature loss of deciduous teeth by the age of 6 years.
Genetic and environmental risk factors for chronic periodontitis and
aggressive periodontitis. Periodontol.
actinomycetemcomitans, which is a causative microorganism in
aggressive periodontitis and its colonization may occur more readily in an environment containing lactoferrin with low iron levels and depressed level of iron found in lactoferrin maybe resulted from both the iron-sequestering pathogenic bacteria and reduced capacity of lactoferrin to bind iron in the saliva of
aggressive periodontitis patients [37, 79]"
According to this report, the authors concluded that there are common features in both the localized and generalized forms of
aggressive periodontitis. All symptoms can occur at any age in patients who follow regular dental care.
[39], in an analysis of a population-based sample from London, showed that the GC genotype had greater representation in subjects with chronic periodontitis (42%) when compared with subjects with
aggressive periodontitis (26.5%) and control subjects (19.2%) and further suggested that this genotype was associated with an increased risk for periodontal disease.
Role of antibiotics in generalized
aggressive periodontitis: A review of clinical trials in humans.
There is also a case report by Seremidi and co-authors describing the therapeutic management of an 8-year-old child with generalised
aggressive periodontitis. Many medically compromised children are prescribed long term medications and some of these medications can have an effect on dental oral health.
The ORs and 95% CIs were calculated to evaluate the association between IL-10-592 (-590, -597) polymorphisms and susceptibility to chronic or
aggressive periodontitis. Heterogeneity between studies was estimated by [chi square] and [I.sup.2].
Direct examination represented by fresh and Gram stain revealed in patients with
aggressive periodontitis, a predominance of flora especially curved, fusiform motile rods, and motile spirochetes and Gram negative bacilli and coccobacilli Gram negative and Gram-positive filaments (Figure2).
The exclusion criteria for this study encompassed patients afflicted with rheumatoid arthritis, tumors, heart diseases, gross oral pathology, smoking trends, hypertension, and
aggressive periodontitis. Additionally, those patients were not included who took any kind of medicine or drugs and who were afflicted with additional systemic conditions which could potentially impact the progress of periodontal diseases.
