agglutinogen

Bordetella pertussis has some important antigens such as pertussis toxin, adenylate cyclase, fimbriae, agglutinogens, Filamentous Hemagglutinin (FHA), pertactin and Outer Membrane Proteins (OMP).

In some agglutination tests, special agglutinogens have been made by attaching inert particles onto the antigen.

However, the Dutch whole-cell vaccine induces low levels of antibodies against pertussis toxin and filamentous hemagglutinin and high levels of antibodies to agglutinogens and pertactin (6).

that has an acellular pertussis component with the following four antigens: agglutinogens (FIM), pertactin (PRN), filamentous hemagglutinin (FHA), and pertussis toxin (PT).

Potential vaccine-target antigens important in disease production include (1) pertussis toxin (lymphocytosis-prorooting factor), which interferes with immune-cell function, contributes to ciliary damage, and aids in attachment to respiratory epithelium; (2) filamentous hemagglutinin, which helps the bacteria attach to cilia of the respiratory tract; (3) pertactin (69-kDa protein), which also enhances bacterial attachment to cilia; and (4) agglutinogens, which may aid persistent attachment to cilia.