9 06/20/16 Total aVDPV -- ([section] -- ([section] -- ([section] [section]) [section]) [section]) Abbreviations: AFP = acute flaccid paralysis; AGG = agammaglobulinemia
; aVDPV = ambiguous VDPV; cVDPV = circulating VDPV; IPV = inactivated poliovirus vaccine; iVDPV = immunodeficiency- associated VDPV; OPV = oral poliovirus vaccine; PID = primary immunodeficiency; SCID = severe combined immunodeficiency; XLA = X-linked agammaglobulinemia
Keywords: Bruton type agammaglobulinemia
, Bruton tyrosine Kinase mutation, Whole exome sequencing, Diarrhoea.
For other primary immunodeficiencies provided by the reader, such as the case of X-linked agammaglobulinemia
, this is a congenital disease that affects males and involves B lymphocytes and plasma cells, which are not the primary immune line in tuberculosis (7), nor does it correspond to our case.
The following conditions/diseases may cause the immune system to be compromised and/or suppressed: Transplantation or Immunosuppressant patients, Chemotherapy/Cancer patients, Overwhelming infection, Poor nutrition, AIDS/HIV, Primary Immune Deficiency, Selective IgA Deficiency, Common Variable Immunodeficiency, X-Linked Agammaglobulinemia
, Chronic Granulomatous Disease, Hyper-IgM Syndrome, Severe Combined Immunodeficiency Disease (SCID), and some newborns diabetes.
, congenital, acquired and transient forms.
Previously, scientists have always thought that BTK is important primarily in antibody production due to observations made of an inherited genetic disorder in humans called X-linked Agammaglobulinemia
Patients with CVID show hypo gammaglobulinaemia in the presence of normal or nearnormal B cell counts which has been named agammaglobulinemia
with B cells.
This was the first documented case of agammaglobulinemia
, one of the more common types of PIs.
In humans, btk is the tyrosine kinase that is deficient in Bruton's X-linked recessive agammaglobulinemia
1-3) The predominant symptomatic forms of PADs are common variable immunodeficiency (CVID), X-linked agammaglobulinemia
(XLA), and Hyper IgM syndromes (HIGM).
Drug reaction to ceftriaksone in a child with X-linked agammaglobulinemia
Zenome T, Souillet G: X linked Agammaglobulinemia
presenting as Pseudomonas aeruginosa septicemia.
Sepsis caused by Veillonella parvula infection in a 17-year old patient with X-linked agammaglobulinemia
HIV infection, systemic lupus erythematosus, lymphoproliferative disorders, myelodysplasia, agammaglobulinemia
or hypogammaglobulinemia, drug-induced thrombocytopenia, alloimmune thrombocytopenia, congenital hereditary nonimmune thrombocytopenia) .