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Recent evidence that FES of cutaneous afferent pathways is effective in modulating the generation of stepping in cats and humans with SCI [44-45] could indicate that applied stimulation may enhance afferent modulation of spinal circuitry.
This seminal discovery has had a major impact on our understanding of the biology of obesity, describing some of the key afferent pathways in body weight regulation active in man.
It has been suggested that SNM inhibits bladder afferent activities through its action on somatic afferent pathways and thereby blocks abnormal sensory input to the spinal cord and brain.
Differential role of inhibition in habituation of two independent afferent pathways to a common motor output.
Psychophysical and Physiological Evidence for Parallel Afferent Pathways Mediating the Sensation of Itch.