Neuroplasticity is implicated in causing both NDO and AD, mediated by reformation of spinal reflex arcs and bladder afferent neurons
Gastroprotective action of lafutidine mediated by capsaicin-sensitive afferent neurons
without interaction with TRPV1 and involvement of endogenous prostaglandins.
Here we focused on the transmitter used by the afferent neurons
for the escape swim circuit, the S-cells.
SA13353 (1-[2-(1-Adamantyl)ethyl]-1-pentyl-3-[3-(4-pyridyl)propyl]urea) inhibits TNF-alpha production through the activation of capsaicin-sensitive afferent neurons
mediated via transient receptor potential vanilloid 1 in vivo.
Injured afferent neurons
produce different neuropeptides to the ones they normally produce.
Similarly in tissue trauma or surgery, release of other mediators of pain like 5HT, along with substance P may sensitize primary afferent neurons
causing pain in cases of nerve entrapment pain or scar pain.
Despite having damaged afferent neurons
, the efferent pathway is still intact allowing pupil constriction in both eyes.
6-8) It is well known that ECM nourishment can sequester and modulate stem cell niches along with synbiotic protein peptide formats to modulate stem cell niches and that afferent neurons
can accomplish some astounding feats of regeneration and neurogenesis.
Inability to sense pain and absence of hidrosis in the patients arise from absence of sympathetic nerve supply of the afferent neurons
of pain and eccrine sweat glands due to tissue damage.
carry neural signals toward the CNS.
Hunger is an intensely motivational state and the complicated picture of how it is regulated has been made more finely detailed again with the exciting discovery of these specific afferent neurons
that are so directly involved with triggering it.
0] represents A[alpha]/[beta] afferent neurons
(intermediate conducting fibers associated with mechanoreceptors) (22,24,25).
Nociceptive pain is defined as pain resulting from the on-going activation of primary afferent neurons
by noxious stimuli (McCaffery & Pasero, 1999).
This analgesic function is due to its capability of depleting substance P stores from the primary afferent neurons
, eventually relieving pain in conditions like peripheral arthritis.
Hyperpolarizing potentials have been described in the squid stellate ganglion (Miledi, 1972), in secondary hair cells and afferent neurons
of the squid statocyst (Williamson, 1989), and in central neurons of the cuttlefish (Chrachri and Williamson, 2003).