IHC: inner hair cell; OHC: outer hair cell; ISBs: inner spiral bundles; ANFs: afferent nerve
Similarly, in a model of OA pain, local administration of CB1 agonist ACEA reduced mechanosensitivity of afferent nerve
fibers, suppressing nociceptive transmission in OA and healthy rat knee joints.
The peripheral pathway of GI visceral pain mainly refers to the primary sensory neuron stage of signal transmission through primary afferent nerve
fibers to the spinal DRG after noxious stimulation acting on the receptors in the GI mucosa.
The changes in gene expression in the DRG suggest that the primary afferent nerve
fibers may be affected by NP.
The etiology of NP remains unknown, although it is thought to be a neuropathic itch caused by afferent nerve
Amino glycosides including streptomycin have been found to cause modulation of the release of excitatory neurotransmitters from primary afferent nerve
proposed a model of AD in which increased NGF in the injured cord stimulates primary afferent nerve
sprouting, thus amplifying spinal sympathetic reflexes and promoting dysreflexia .
This pathologic change prompts the surviving primary afferent nerve
fibers, after being damaged, and to form new connections - the regeneration of the central synapse with the bone pain signal transmitting neurons.
Impaired intestinal afferent nerve
satiety signalling and vagal afferent excitability in diet induced obesity in the mouse.
The characterization of afferent nerve
fiber function using quantitative sensory testing and histamine-induced flare analysis showed that PHN is associated with damage of afferent fibers.
The mental nerve (MN) is a general somatic afferent nerve
that provides sensation to the lip, chin, and gingival tissue.
The rationale for this approach is that by interrupting the neural pathways to and from the scrotal contents, this decreases afferent nerve
stimulation and downregulates pain centres.
By cutting the afferent nerve
fibres in rats, a team of scientists led by Urs Meyer, a researcher in the group of ETH Zurich professor Wolfgang Langhans, turned this two-way communication into a one-way street, enabling the researchers to get to the bottom of the role played by gut instinct.
For example, a contracted muscle may irritate its own afferent nerve
, which in turn may stimulate its own motor nerve.
The responses induced by acupuncture-like stimulation are reflexes in which cutaneous and/or muscle somatic afferent nerve
fibers of the afferent limb, autonomic efferent nerve fibers of the efferent limb, and the spinal cord and/or the brain stem of the reflex centers workin a complex way .