sepsis

Three to six hours before aerosol infection, groups of five mice were administered with 250 [micro]L/mouse of test cynomolgus macaque serum, positive control vaccinated human serum, or as a negative control nonvaccinated human serum via the intraperitoneal route.

In addition, an experimental aerosol infection was conducted by using the parental strain of the most recent avH1N1 strain contained in a European swine inluenza vaccine (A/sw/Haselunne/IDT2617/2003).

After aerosol infection, the survival of BALB/c mice has been reported to be similar to C57BL/6 (resistant) mice (5).

Aerosol infection of calves and mice with Salmonella Typhimurium.

Extrapolation of data from human aerosol infection studies has estimated that lung deposition of a single colony forming unit (CFU) may be sufficient to establish infection [3].