Melanosis and squamous cell neoplasms of the upper
aerodigestive tract in Japanese alcoholic men.
As such, Slaughter's observation of frequent synchronous or metachronous tumors in the
aerodigestive tract is expected, based on elevated risk from carcinogen exposure alone.
In most cases (>80%), the foreign bodies would pass without any intervention; however, in some cases non-operative interventions (10-20%) would be required and in rare cases, surgical intervention (~~1%) is advocated.4-6 A thorough examination of the upper
aerodigestive tract may be sufficient to locate and remove the embedded foreign body.
Suarez, "Sarcomatoid carcinomas of the upper
aerodigestive tracts," Advances in Anatomic Pathology, vol.
Surgery, or combined radiotherapy and surgery, are the optimal therapeutic options for the upper
aerodigestive tract. (3) Resection is the optimal management for colonic plasmacytoma.
Table 1: Radiological grading of upper
aerodigestive tract cancers Site Radiological Total I II III IVa IVb IVc Glottis 13 0 4 0 0 2 19 Oral cavity 0 0 2 5 4 0 11 Oropharynx 2 0 2 0 2 0 6 Nasopharynx 0 5 2 0 0 0 7 Hypopharynx 0 0 0 3 3 2 8 Salivary gland 0 2 2 2 0 0 6 Maxillary sinus 0 0 0 2 1 0 3 Total 15 7 12 12 10 4 60 P = 0.0001.
Conclusion: IDL shows higher diagnostic accuracy than neck X-Rays for detection of fishbone in upper
aerodigestive tract. Neck X-rays are more useful for impacted foreign bodies in oesophagus.
Epidemiological studies have suggested that reduced folate levels in the body increase the risk of several types of cancer, including those of the upper
aerodigestive tract, colon/rectum, and breast (Kim 2005).
Patients with squamous cell carcinomas of the head and neck (HNSCC) region show a predisposition to developing second primary squamous cell carcinomas in the
aerodigestive tract [1-3].
Spindle-cell carcinoma of the upper
aerodigestive tract mucosa.
Alcohol is known to be carcinogenic to humans in the upper
aerodigestive tract, liver, colorectum, and the female breast.
Although initially proposed as a palliative tool in the management of end-stage esophageal or bronchogenic carcinoma, it has emerged as a modality which can effectively treat early as well as advanced endoluminal tumors, PDT has been incorporated into all aspects of our practice, including palliation, induction therapy, and definitive intervention for early-stage cancers of the
aerodigestive tract. We have been pleased by our experience and are excited about the future impact photodynamic therapy will have on therapeutic options for our cancer patients." *
"The findings from this large network of Italian case-control studies have provided support for an apparent protective role of flavanones on upper
aerodigestive tract cancers; flavonols, anthocyanidins, and proanthocyanidins on colorectal cancer; flavonols and flavones on breast cancer; isoflavones on ovarian cancer; and flavonols on renal cancer," the authors conclude.
The MRI confirmed the ICA ectasia (often referred to as tonsillar loop) which manifested the asymmetry of the contour of the nasopharynx with prominence and fullness on the left just below the fossa of Rosenmuller.(Figure 2) There was no evidence of any mucosal abnormalities of nasopharynx or of the remainder of upper
aerodigestive tract. No other pathological lesion was noted and the biopsy was cancelled.
