adrenal cortex

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Adrenocortical carcinoma is a rare tumour and has an incidence of 0.5-2 per million per year.1 Adrenocortical carcinoma can occur at any age but bimodal distribution is more frequent.
Malignant adrenal masses, primary adrenocortical carcinoma, retroperitoneal teratomas and mesenchymal tumors were considered in the differential diagnosis.
This case represented an unusual combination of adrenocortical adenoma and pheochromocytoma.
To reduce the risk of hypokalemia, evaluation of adrenocortical insufficiency and concomitant drugs is required.
The prevalence of adrenocortical carcinomas among adrenal incidentalomas ranges from 1.2 to 12% among different studies [5].
PA can be caused by idiopathic unilateral or bilateral adrenal hyperplasia, aldosterone-producing adenomas (APAs), pure aldosterone-producing adrenocortical carcinomas, familial hyperaldosteronism, and, in rare cases, by ovarian tumors.
Two patients had achalasia, alacrima and adrenocortical deficiency as well as neurologic and autonomic dysfunction, third patient had achalasia and neurologic dysfunction only.
Patient selection criteria: Critically ill patients of various diseases admitted to Medical ICU and were having or suspected of having some degree of adrenocortical dysfunction on the basis of prolonged hypotension for more than 6 hrs.
Feminizing adrenocortical carcinomas are defined as malignant tumors with estrogens overproduction with or without other adrenocortical hormones.
We report a case of PA due to adrenocortical adenoma (Conn's syndrome) coexisting with Graves' disease in the same patient and review the available literature in view of identifying possible associations.
Li-Fraumeni syndrome (LFS) is associated with a high lifetime risk of multiple primary cancers including soft tissue sarcoma, osteosarcoma, premenopausal breast cancer, brain tumors, adrenocortical carcinoma (ACC), and leukemias.
* Suppression of the adrenocortical hormone: This can emerge as a result of the inhibition of 11-p hydroxylase enzyme.