In their experiments, the scientists traced the neural circuitry that links areas of the cerebral cortex to the adrenal medulla
(the inner part of the adrenal gland, which is located above each kidney).
Pheochromocytomas are tumors of the adrenal medulla
that produce and usually secrete large amounts of catecholamines often associated with high fatality rates when undiagnosed (1).
Maternal perinatal undernutrition has long-Term consequences on morphology, function and gene expression of the adrenal medulla
in the adult male rat.
In spite of many advances taking place in the evaluation of tumours of adrenal medulla
, careful gross examination and histological interpretation of H and E sections still remain the fulcrum basing on which an accurate diagnosis is made.
Paraganglioma originates from chromaffin cells of adrenal medulla
and autonomic paraganglia, which are derived from the neural crest cells.
This could be because the adrenal medulla
and sympathetic ganglia are completely differentiated by 10 to 15 years of age.
Catecholamines (adrenaline (A) and noradrenaline (NA)) are released from sympathetic nervous fibers endings (NA) and adrenal medulla
(A and NA) (1, 2).
In the adrenal medulla
, norepinephrine is converted to epinephrine in the presence of phenylethanolamine-N-methyltransferase.
While the primary goal of the project is to characterize the molecular mechanisms underlying acute O2 sensing by arterial chemoreceptors (carotid body CB- and adrenal medulla
AM-), we will also extend our study to other organs (e.
The sites of origin of ganglioneuroblastoma include adrenal medulla
, extra-adrenal retroperitoneum, posterior mediastinum, the neck, and pelvis.
Pheochromocytoma (PHEO), although rare, is a tumor of the chromaffin tissue with 90% localization in the adrenal medulla
In contrast, it mostly arises from VIP secreting tumor originating from the neural crest cells in the adrenal medulla
or sympathetic ganglia in children (4).
Phaeochromocytomas are neuro-endocrine catecholamine-secreting tumours that arise from chromaffin cells of the adrenal medulla
or sympathetic paraganglia.
Pheochromocytomas are rare catecholamine producing neuroendocrine tumors typically located in the adrenal medulla
or along the sympathetic ganglia.
The mechanism that allows a group of cells derived from the neural crests to migrate in the upper region of the kidney, such as adrenal medulla
, is unclear; other cells developing from the celomic epithelium will completely surround the medulla, such as adrenal cortex.