adnexa

Adnectins are a proprietary class of targeted biologics developed by Adnexus.

Companies Listed AbbVie Abgenix (part of Amgen) Ablynx Actavis AdAlta ADC Therapeutics Adnexus (acquired by Bristol-Myers Squibb) Affibody Affimed Therapeutics Agensys Albany Molecular Research Inc.

Abbott Laboratories Acucela Adnexus Advanced Cell Technology (now Ocata Therapeutics) Alcon Aldexa (previously Neuron Systems Inc.

John Mendlein, Executive Chairman and CEO of aTyr Pharma and former CEO of Adnexus Therapeutics, have joined the Board of Directors.

Past Polaris-backed successes include: Adnexus (acquired by BMS), Advanced Inhalation Research (acquired by Alkermes), Akamai Technologies (AKAM), Allaire (ALLR, acquired by Adobe), Alnylam Pharmaceuticals (ALNY), Asthmatx (acquired by Boston Scientific), Athenix (acquired by Bayer), Glycofi (acquired by Merck), Internet Brands (acquired by Hellman and Friedman), Ironwood (IRWD), LogMeIn (LOGM), Momenta Pharmaceuticals (MNTA), Powersoft (PWRS, acquired by Sybase), Solidworks, and TechTarget (TTGT).

Flagship's portfolio ventures include: Accuri Cytometers (acquired by Becton Dickinson), Adnexus (acquired by Bristol-Myers Squibb), Acceleron (NASDAQ: XLRN), Agios (NASDAQ: AGIO), BIND Therapeutics (NASDAQ: BIND), Concert Pharmaceuticals (NASDAQ: CNCE), Eleven Biotherapeutics (NASDAQ: EBIO), Hypnion (acquired by Eli Lilly), Morphotek (acquired by Eisai), Receptos (NASDAQ: RCPT), T2 Biosystems (NASDAQ: TTOO) and Tetraphase (NASDAQ: TTPH).

Companies Listed Abbott Laboratories Acucela Adnexus Advanced Cell Technologies Alcon Alexion Alimera Sciences Alkeus Pharmaceuticals Allegro Ophthalmics Allergan American Academy of Ophthalmology American Society of Retina Specialists Amgen Ampio Pharmaceuticals Applied Genetic Technologies Association for Research in Vision and Ophthalmology (ARVO) AstraZeneca Athenagen Atlantis Pharma ATON Pharma Avalanche Biotechnologies Bausch & Lomb Bayer Bayer Yakuhin (Bayer subsidiary) Biogen Idec Biotime

Several examples of successful portfolio ventures include, Acceleron Pharma, Agios, Accuri Cytometers, AVEO, Morphotek, Adnexus, and Joule Unlimited.

Regeneron - Sanofi - Amgen - Pfizer - Novartis - Alnylam - Isis Pharmaceuticals - Bristol Myers Squibb - Santaris - Adnexus - Alder Biopharmaceuticals - AFFiRiS - Serometrix - Shifa - Idera - Merck