"Liposomal encapsulation enhances and prolongs the anti-inflammatory effects of water-soluble dexamethasone phosphate in experimental adjuvant arthritis
." Arthritis research & therapy, 12(4): p.R147 (2010).
Pathway to adjuvant arthritis
. J Fed Proc 1976;35(13):2442-6.
Abbreviations miRNA: MicroRNA UTR: Untranslated region FLS: Fibroblast-like synoviocyte RA: Rheumatoid arthritis RF: Rheumatoid factor MRI: Magnetic resonance imaging DMARD: Disease-modifying anti-RA drugs TNF: Tumor necrosis factor LPS: Lipopolysaccharide IL: Interleukin AA: Adjuvant arthritis
MMP: Metalloproteinase NF-[kappa]B: Nuclear factor-kappa B TAB: TGF-[beta]-activated kinase 1/MAP3K7 binding protein IKK: Inhibitor of nuclear factor kappa B kinase TRAF2: TNF receptor associated factor 2 TNFAIP-3 : Tumor necrosis factor a-induced protein 3 5-azaC: 5-Aza-2'-deoxycytidine SCID mice: Severe combined immunodecifient mice.
Zee et al., "Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis
," Nature, vol.
Laboratory Animals and Adjuvant Arthritis
. After obtaining 40 2-month-old adult male Wistar rats weighing between 180 and 200 g from the Tianjin Laboratory Animal Centre (Tianjin, China), conventional environmental conditions were used for maintenance: namely, a 12-hour light/dark cycle, 25 [+ or -] 2[degrees]C, and 50% humidity.
(1) The rats were randomly divided into seven groups, each of which included ten animals, that is, control group (C), adjuvant arthritis
group (AA), dexamethasone acetate group (DMA), Qing Peng ointment group (QPO), low dose Wuwei-Ganlu-YaoyuKeli group (WGYKl), moderate dose Wuwei-GanluYaoyu-Keli group (WGYKm), and high dose WuweiGanlu-Yaoyu-Keli group (WGYKh).
and Carrageenan Induced Hind Paw Edema.
Another study evaluated the effects of TQ on polyarthritis index and pain response score in Freund's adjuvant arthritis
(AA) in rats shares many pathologic characteristics with RA suffered in humans, such as extremities swelling, synovium hyperplasia and cartilage degradation.
The anti-inflammatory effect of sterically stabilised nanoliposomes of methyl prednisolone hemisuccinate and betamethasone hemisuccinate was analysed in adjuvant arthritis
by Ulmansky et al.
Rat carrageenin paw edema was used as a model of acute inflammation and mycobacterium induced adjuvant arthritis
as a model of chronic inflammation.
VIII: differences in immunopathogenesis between type II collagen arthritis and adjuvant arthritis
," Agents and Actions, vol.
Conclusions: Our observations suggest that GS is not able to suppress the progression of adjuvant arthritis
in OA with effusion of knee osteoarthritis.
In a rat adjuvant arthritis
model, caffeine as well as theophylline (another non-selective adenosine receptor antagonist) both reversed the beneficial effects of MTX treatment.
The anti-inflammatory potential of ethanolic extract of the plant has been explored in adjuvant arthritis
(Kripa et al., 2011).