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Nourianz (istradefylline) is an adenosine receptor antagonist indicated as adjunctive treatment to levodopa/carbidopa in adult patients with Parkinson's disease experiencing "off" episodes.
The phase two study is a multicentre, randomised, double-blind, placebo-controlled three-arm study to evaluate the safety and tolerability of multiple oral doses of REL-1017 25mg and 50mg as adjunctive therapy in the treatment of patients diagnosed with major depressive disorder.
In the article entitled "A Cost-Effectiveness Model for Adjunctive Smoked Cannabis in the Treatment of Chronic Neuropathic Pain," David Grelotti and coauthors from UCSD, University of California Center for Medicinal Cannabis Research (San Diego), and Columbia University (New York, NY) created a computer simulation to compare the cost of usual first-, second-, and third-line care with those supplemented with smoked cannabis.
According to the company, LYRICA is currently approved in the US for fibromyalgia, diabetic nerve pain, spinal cord injury nerve pain and pain after shingles in adults as well as approved as adjunctive therapy for the treatment of partial onset seizures in patients four years of age and older.
Maurizio Fava, M.D., from Harvard Medical School in Boston, and colleagues report on the efficacy and safety of BUP/SAM as adjunctive treatment in patients with MDD and inadequate response to ADT in two phase 3 randomized studies (FORWARD-4 and FORWARD-5).
Celecoxib as adjunctive treatment to risperidone in children with autistic disorder: a randomized, double-blind, placebo-controlled trial.
"Removal without adjunctive therapy is a guaranteed failure--about 100% of the time in my experience.
EXIST-3 is the first Phase III study to demonstrate the significant benefit of adjunctive Afinitor DISPERZ in the treatment of patients with TSC-associated partial-onset seizures.
The number needed to treat for response was approximately six in favor of adjunctive L-methylfolate at 15mg/day.
(7) Adjunctive antidepressants can also be ineffective: A decade ago, the Systematic Treatment Enhancement Program for Bipolar Disorder, or STEP-BD, showed that antidepressants, when added to mood stabilizers, were no more effective than placebo in treating bipolar disorder.
We conducted a retrospective study of the use of cidofovir and the measles, mumps, and rubella (MMR) vaccineas adjunctive treatments to lesion debridement in patients with recurrent respiratory papillomatosis (RRP).Our study population was made up of 15 children--7 boys and 8 girls, aged 1 to 16 years at diagnosis (mean: 6.2)--with pathologically confirmed RRP who had been followed for at least 1 year.
[4,6] Recent studies in China and elsewhere have assessed the effectiveness of adjunctive treatment with metformin, [7,8] memantine, [9] nizatidine, [10] and topiramate [11] to reduce or eliminate antipsychotic-induced weight gain and other metabolic changes in patients with schizophrenia.
announced that the FDA has approved Fycompa (perampanel) CIII for adjunctive therapy in the treatment of primary generalized tonic-clonic (PGTC) seizures, one of the most common and severe forms of generalized seizures with a high incidence of morbidity and mortality.