, osteoblasts and chondrocytes are distinct from another production line in the bone marrow--the hematopoietic system--that makes red blood cells, blood-clotting cells and cells of the immune system.
Curcumin inhibits adipocyte
differentiation through modulation of mitotic clonal expansion.
Presumably owing to the higher sensitivity of ECs compared to adipogenic differentiated ASCs (diffASCs), current approaches are in most cases based on either the addition of adipocyte
factors to EC medium or on a 1:1 mixture of EC and adipocyte
media (Pellegrinelli et al., 2013; Yao et al., 2013a,b; Aubin et al., 2015; Arnal-Pastor et al., 2016).
FTO obesity risk variants are linked to adipocyte
IRX3 expression and BMI of children - Relevance of FTO variants to defend body weight in lean children?
MAPK phosphatase-1 (MKP-1) downregulates the expression of p42/p44 MAPK and plays an important role in adipocyte
The immortalized brown adipocyte
cell line (IM-BAT) was constructed and a gift by Dr.
Lipocalin 2 (LCN2), also a secretory protein of adipocyte
, has an important function in hematopoiesis.
Therefore, the main purpose of this study was to test the hypothesis that SAT and VAT adipocyte
gene expression of DIO2 differs between obese and lean human AT and that these differences will relate to (1) insulin resistance and (2) expression of genes involved in mitochondrial function, fatty acid flux, and inflammation.
The remodeling of adipose tissue causes adipocytes
to decrease in size, with increased size variation and a more rounded shape.
Effects of Hinokitiol on the Adipocyte
Differentiation of MSCs.
culture, we found that TLR9 positively promoted KLF4 expression, and while under different concentrations of PA, the TLR9 expression level has no significant difference.
Failure of adipocyte
differentiation causes type II diabetes mellitus?
Dietary treatment of rodents with resveratrol protected mice against HFD-induced body weight gain and obesity by increasing energy expenditure which was partly mediated by stimulating intracellular mitochondrial functions (fatty acid oxidation) in adipose tissue and by the suppression of fatty acid synthesis [88-90] and by inducing brown-like adipocyte
formation in white adipose [91-94].
Zhang et al., "Effects of prostaglandin F2a on adipocyte
biology relevant to graves' orbitopathy," Thyroid, vol.
Although multiple molecular processes are involved in increasing adipose tissue mass, obesity can be a result of both an increase in adipocyte
size as a consequence of increased triacylglycerol content within the fat cell and an increased number of adipocytes
resulting from differentiation of precursor cells .