junction

It is also found in adherent junctions, forming a complex with Ecadherin, a-catenin, and actin filaments of the cytoskeleton [1].

(14,15) Vinculin is a functionally related protein of adherent junctions, structures by which cells make contacts with neighboring cells or to the extracellular matrix.

The Krt6 gene is frequently induced in wound edges in which cell-cell contacts, such as adherent junctions, are lost [13], and E6 PDZ-binding motif binds and degrades scaffold proteins that participate in adherent junctions formation [14,15].