Assist in studies to optimize the manufacture of adenoviral
and MVA-vectored vaccines; such as evaluation of alternative systems, host or vector gene deletions or insertions, viral culture yield, systems for viral growth, etc.
Immune suppression is one recognized risk factor for more severe adenoviral
disease; underlying heart and lung disease are others.
(22) reported that herpetic keratoconjunctivitis can often be confused with adenoviral
EKC due to similarities in their clinical course and common iVCM findings.
genome detected by myocardial biopsy was the only potential cause, as all other examinations including coronary angiography, echocardiography, and cardiac magnetic resonance imaging were completely normal.
Indeed, HNP-1 inhibited the adenoviral
infection of 293 cells in a concentration range of 2 to 50 mg/ml .
We have previously shown that transplantation of hUCB-MCs, transduced by an adenovirus, carrying the gene gdnf and a direct delivery of adenoviral
vectors encoding a similar gene promotes SC migration to the spinal cord .
infection is slightly toxic to HSCs, however, so the researchers developed an alternative approach in which purified BCL-XL could be introduced directly into isolated HSCs.
Potent effect of adenoviral
vector expressing short hairpin RNA targeting ribonucleotide reductase large subunit M1 on cell viability and chemotherapeutic sensitivity to gemcitabine in non-small cell lung cancer cells.
Diagnostico de conjuntivite adenoviral
pelo RPS Adenodetector (2007).
Intrexon said it plans to integrate and expand upon GenVec's expertise in adenoviral
vectors and cGMP drug product manufacturing to enhance its broad gene transfer capabilities that encompass multiple viral and non-viral platforms.
The eight selections that make up the main body of the text are devoted to adenovirus biology and development as a gene delivery vector, innate and adaptive immune responses to adenovirus, helper-dependent adenoviral
vectors for cell and gene therapy, and a wide variety of other related subjects.
There were 2(0.53%) patients each of adenoviral
conjunctivitis and papilloedema.
 revealed that adenoviral
delivery of TGF-[beta]1 gene into chondrocytes led to a marked increase in collagen synthesis.
Three adenovirus vectors transduced P0 and P4 inner ear, with different specificities and expression levels that are dependent on the type of adenoviral
vectors and the age of mice.
used a combined promoter system of adenoviral
vectors in order to induce maturation changes in DCs.