Sarcoplasmic reticulum adenosine triphosphatase
overexpression in the L-type [Ca.sup.2+] channel mouse results in cardiomyopathy and [Ca.sup.2+] -induced arrhythmogenesis.
A less certain diagnosis can be made if biopsy reveals characteristic morphology and if two or more of the following are present on staining: characteristic peanut lectin binding, S-100 protein, alpha-D-mannosidase, and adenosine triphosphatase
. A weaker presumptive diagnosis can be made if histologic characteristics are consistent with those reported in the literature.
Calcium and cAMP activate the enzyme hydrogen, potassium adenosine triphosphatase
(ATPase), also known as the proton pump, to move a hydrogen ion from the parietal cell into the gastric lumen.
They investigated and enzyme called sodium- and potassium-dependent adenosine triphosphatase
([Na.sup.+.,K.sup.+.-ATPase]) in two strains of rats -- one that becomes hypertensive in response to a high-salt diet and one that retains normal blood pressure despite a high-salt diet.
The rapid influx of potassium is due to increased activity of sodium potassium adenosine triphosphatase
pump (Na+ K+ ATPase).7 Increased Na+ K+ ATPase activity is augmented by insulin excess, increased adrenergic response and high circulating levels of thyroid hormones in patients of hyperthyroidism.
These observations bring us to the conclusion that hawthorn and digoxin probably bind at the same site of Na, K adenosine triphosphatase
and probably compete for binding sites and that hawthorn appears to be more potent, causing further concern for individuals who are taking digoxin and who may self-medicated with hawthorn.
Sections have been submitted to mATPase (myofibrillar adenosine triphosphatase
) reaction (Pette & Staron) after pre-incubations in pH of 4.3, 4.5 (Brooke & Kaiser, 1970) and 10.3 (Guth & Samaha, 1970), and fibers types were identified and counted.