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(biochemistry) a nucleoside that is a structural component of nucleic acids

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References in periodicals archive ?
The researchers then sought to see if they could undo the destructive effects of the disease by increasing the adenosine levels.
"These new additions to our Adenosine product line provide clinicians in hospitals and cardiology centers with affordable generic alternatives to care for their patients and reflect Fresenius Kabi's significant investment in the ongoing expansion of our Simplist prefilled syringe portfolio," said John Ducker, president and chief executive officer of Fresenius Kabi USA.
Adenosine deaminase ADA is an enzyme found in purine salvage pathways.
In an in vitro experiment,[2] ticagrelor was shown to increase the concentration of extracellular adenosine by inhibiting its uptake by red blood cells.
Adenosine deaminase (ADA) is an enzyme which is involved in purine metabolism in which it is responsible for conversation of adenosine and deoxyadenosine to inosine and deoxyinosine respectively resulting in release of ammonia.
Caffeine's well-documented physiological effect on alertness originates from its actions as an antagonist of adenosine receptors in the brain.
ADO levels can be regulated by intracellular and extracellular mechanisms, through the action of (i) nucleoside transporters, namely, equilibrative nucleoside transporters (ENT1, ENT2, ENT3, and ENT4) and concentrative nucleoside transporters (CNT1, CNT2, and CNT3), that are able to transport ADO inside the cells [2, 11] and (ii) adenosine deaminase (ADA1 and ADA2), which is expressed by different cell populations and is able to convert ADO into inosine [12, 13].
Human [A.sub.3] adenosine receptor-expressing CHO-K1 cells (CHO-K1-h[A.sub.3]AR) were purchased from PerkinElmer (ValiScreen[R] GPCR cell line) and were grown using Ham's F12 supplemented with 10% FCS, 2 mM L-glutamine, penicillin (100 U/M), streptomycin (100 [micro]g/mL), and 0.4 mg/mL G418.
Adenosine was chosen as the internal reference substance, and the relative correction factors (RCF) between the internal marker and test specimen were used to calculate the other four components.
Many animal and cell experiments disclosed that ticagrelor could inhibit the cellular uptake of adenosine through equilibrative nucleoside transporter 1 leading to the increase of adenosine plasma concentration (APC) [4].
TEHRAN (FNA)- Scientists discovered that curtailing activity of the neuromodulator adenosine extends the critical period of auditory learning in mice and offers promising results for humans.
Adenosine is a key endogenous signalling molecule produced by all types of cells, and documented as a major local regulator of tissue function.
The Role of [A.sub.2A] Adenosine Receptor in Vascular Tone Regulation
Adenosine was used as an alternative to create temporary heart block, enabling accurate valve deployment during the cardiac arrest period.
Adenosine is a non -toxic purine abundant in meat and sugar beets, was reported to provide health benefits including antioxidant, anti-inflammatory effects as well as vascular protective properties.