[down arrow] Neointima proliferation (2008) [down arrow] free radical formation [down arrow] LOX-1 expression DPPH, l,l-diphenyl-2-picrylhydrazyl; LOX-1, lectin-like oxyLDL receptor-1; ACAT2, acyl CoA
: cholesterol O-acyltransferase; MTP, microsomal triglyceride transfer pro-tein; VLDL-C, very low density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol; HMG-CoA, 3-hydroxy-3- methylglutaryl-Co-enzyme A; HMGR, 3-hydroxy-3-methyl-glutaryl flavanones enriched fraction.
Since C75-CoA prepared by chemical synthesis  yields a chemical structure very different from that obtained enzymatically in vivo, the C75-CoA was prepared by enzymatic synthesis with long chain acyl CoA
synthase as described in [39, 40].
TMS tests: Phenylketonuria, Homocystinura, Maple Syrup Urine Disease, Arginino Succinic Aciduria, Citrullinemia, Propionic Acidemia, Methyl Malonic Acidemia, Isovaleric Acidemia, Beta Ketothiolase deficiency, Glutaric Aciduria types 1 & 2, Medium Chain Acyl-CoA Dehydrogenase deficiency, Very Long Chain Acyl CoA
Dehydrogenase deficiency, HMG-CoA Lyase deficiency.
Luca's parents knew he was at high risk of developing the rare MCAD (Medium-chain acyl CoA
dehydrogenase), which affects the metabolism, because of a family history which saw one member killed by the illness.
Predictive value, clinical status and genotype of medium-chain acyl CoA
dehydrogenase deficiency (MCADD) ascertained by screening at one week of age using electrospray tandem mass spectrometry of underivatized blood spots: findings from a UK multicentre trial.
Medium Chain Acyl CoA
Dehydrogenase Deficiency (MCADD) can be easily managed once diagnosed but often the first sign is when the sufferer is taken seriously ill.
Normal functioning of the CPT system is required to ensure long chain fatty acyl CoA
is transported to the mitochondrial matrix where it is needed for [beta]-oxidation.
Steady-state levels of acyl CoA
oxidase (ACO); 3-hydroxy, 3-methylglutaryl CoA reductase (HMG-R); and apolipoprotein A-I (Apo A-I) mRNA were examined after 24-hour incubation in the absence (control) or presence of 100 [micro]m each of linoleic acid (LA), cis-9, traps-11 CLA or traps-10, cis-12 CLA.
Molecular cloning of the peroxisome proliferators-induced 46kDa cytosolic acyl CoA
thioesterase from mouse and rat liver--recombinant expression in Escherichia coil, tissue expression and nutritional regulation.
The major diagnoses were fatty acid oxidation defects, particularly medium-chain acyl CoA