Atelectasis and pneumonia in acute spinal cord injury
. Arch Phys Med Rehabil 1990; 71: 197-200.
The Neuro-Spinal Scaffold, an investigational device, has received a Humanitarian Use Device designation and is currently being studied in an Investigational Device Exemption pilot study for the treatment of patients with complete (AIS A) traumatic acute spinal cord injury
Pathophysiology and pharmacologic treatment of acute spinal cord injury
. Spine J 2004;4:451-464.
Xu used methylprednisolone sodium succinate shock therapy in the treatment of acute spinal cord injury
and found that high dose methylprednisolone sodium succinate shock therapy was effective, safe and reliable in treating acute spinal cord injury24, which was consistent with the finding of this study.
(NYSE:AST) announced that the independent Data Monitoring Committee (DMC) for the company's SCiStar Phase 1/2a study of AST-OPC1 in acute spinal cord injury
has completed a regularly scheduled review of the safety data.
Asterias Biotherapeutics announced that the independent Data Monitoring Committee, or DMC, for the company's SCiStar Phase 1/2a study of AST-OPC1 in acute spinal cord injury
has completed a regularly scheduled review of the safety data from all subjects in the five study cohorts and has recommended that the SCiStar study continue according to protocol to its final data readout.
Neurologic damage developing after acute spinal cord injury
is related with necrosis developing after secondary injury and primary mechanic injury and apoptosis which develops later (Anderson et al., 1982).
MR features of acute spinal cord injury
(SCI) include smooth enlargement of the cord contour, hyperintensity on T2W and hypointensity on T1W, and hemorrhage .
Admission diagnoses were 'acute spinal cord injury
, American Spinal Injury Association (ASIA) A, and complete paraplegia.' A space-occupying lesion in the thoracic spine required investigation.
The Healing of Bone Marrow-Derived Stem Cells on Motor Functions in Acute Spinal Cord Injury
Antioxidant therapies for acute spinal cord injury
. Neurotherapeutics 2011; 8: 152-67.
As Edward Benzel and his colleagues said in 2000, "The reporting of the results of National Acute Spinal Cord Injury
Studies II and III has been incomplete, leaving clinicians in the spinal cord injury community to use or avoid using methylprednisolone in acute SCI on the basis of FAITH rather than a publicly developed scientific consensus".27-35
Following acute spinal cord injury
, surgical implantation of the biodegradable Neuro-Spinal Scaffold within the decompressed and debrided injury epicenter is intended to support appositional healing, thereby reducing post-traumatic cavity formation, sparing white matter, and allowing neural regeneration across the healed wound epicenter.
More than 30 years ago, MP was considered to reduce lipid peroxidation triggered as secondary damage following SCI  and its use is largely justified on the National Acute Spinal Cord Injury
Studies trial II (NASCIS II) [5,6], in which the major finding was that a subgroup of patients treated with 30 mg/kg bolus at hospital admission followed by 5.4 mg/kg/h for the next 23 h starting before 8 h of contusion showed a slight improvement in light touch and pinprick sensation and a very subtle motor improvement.
The role and timing of decompression in acute spinal cord injury
: what do we know?