Improved outcome of pediatric patients with
acute megakaryoblastic leukemia in the AML-BFM 04 trial.
MATERIAL AND METHOD: All
acute megakaryoblastic leukemias diagnosed in the department of pathology, Gandhi medical college Bhopal, in the period of 2003-2012., were included in the study.
Fetal origin of the GATA1 mutation in identical twins with transient myeloproliferative disorder and
acute megakaryoblastic leukemia accompanying Down syndrome.
(2, 3) In addition, there have been rare reports of comparisons of
acute megakaryoblastic leukemia and CML with trisomy 19 presenting with blast crisis.
Acute megakaryoblastic leukemia can be more difficult to distinguish from pure erythroid leukemia.
(5) Occasionally, however, TMD has preceded
acute megakaryoblastic leukemia (AML-M7) after a period of remission lasting several months to years.