We found that hASC decreased proliferation of activated lymphocytes
by downmodulation of surface IL-2 receptor alpha subunit (CD25) expression.
Therefore, this study provides new insights showing that a simple training protocol composed of walking is sufficient to activate immune markers of activated lymphocytes
. Future studies should be designed to investigate the specific mechanism, including joint analyses.
PPRV infects PHA activated lymphocytes
more efficiently than the unstimulated ones.
 This suggests that LUCs represent virally activated lymphocytes
, consistent with our hypothesis that circulating LUCs would be present in higher numbers in individuals with chronic immune stimulation.
The researchers speculated that topical cyclosporin's clinical benefits in ocular rosacea are due to the drug's anti-inflammatory effects, including a cy-closporine-mediated reduction in the number of activated lymphocytes
in the conjunctiva, in combination with stimulation of increased tear production
Active immunity occurs when an individual's own body makes activated lymphocytes
to a particular antigen; therefore, the host's immune system plays an active role in responding to the antigen.
In healthy animals the lymph moves as a seamless river, transporting immune information from one part of the body to another, bringing activated lymphocytes
to areas where they are needed, and helping to remove accumulations of debris and toxins.
But investigators at the University of Alberta, Edmonton, discarded the standard islet-toxic immunosuppressive regimen routinely used in whole-organ transplants in favor of a gentler sirolimus- and tacrolimus-based, corticosteroid-free regimen utilizing daclizumab, a monoclonal antibody directed against the interleukin-2 receptor on activated lymphocytes
. They also boosted the islet dose, infusing islets harvested from two donor pancreases per recipient.
(12) have shown that macrophages, when stimulated, function as a CYSH pump that takes up cystine and releases CYSH, increasing the intracellular GSH level of activated lymphocytes
in the vicinity.
The [C.sub.t] values were 30 and 21 in the resting and activated lymphocytes
An alternative method to measuring the functional activity of lymphocytes is to use flow cytometry to determine the percentage of cells expressing activation-specific antigens (i.e., antigens that are only expressed on activated lymphocytes
The activated lymphocytes
multiply, return to circulation, migrate through the blood stream and cross the endothelial cells lining the capillaries and initiate an inflammatory response.
"I think all you need are a few activated lymphocytes
wandering into the brain ...
Selective binding with S1PR1 is believed to inhibit a specific subset of activated lymphocytes
from migrating to sites of inflammation.
Sullivan, "Activated lymphocytes
during acute Epstein-Barr virus infection," Journal of Immunology, vol.