actinism

Actinic keratosis is a common skin condition that is induced through ultra-violet light damage, resulting in patches of thick, scaly or crusty skin.

KX2-391, also known as KX-01, is a first-in-class dual Src kinase and tubulin polymerization inhibitor in Phase III development as a topical medicinal product for the treatment of actinic keratosis.

An actinic keratosis (AK), also known as a solar keratosis, is a crusty, scaly growth caused by damage from exposure to ultraviolet (UV) radiation.

Chen and Australian colleagues enrolled 386 people in their multicenter, double-blind trial (Oral Nicotinamide to Reduce Actinic Cancer [ONTRAC]).

The report provides comprehensive information on the therapeutics under development for Actinic (Solar) Keratosis, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type.

Topical ingenol mebutate won regulatory approval for the field treatment of actinic keratoses on the strength of four randomized, double-blind placebo-controlled clinical trials, but patients and their physicians need to know how the drug performs in clinical practice.

Porokeratosis, disseminated superficial actinic porokeratosis.

Also there is hyperkeratotic plaque with fissuring seen over right angle mouth; suggestive of actinic cheilitis (fig).

During an average 4-year prospective follow-up conducted at 6-month intervals in the Veterans Affairs Topical Tretinoin Chemoprevention Trial, the 1,131 elderly participants, most of whom were male, developed 3,291 periocular actinic keratoses (AICs).

AR, photosensitive eczema, chronic photosensitive dermatitis, and persistent light reaction are different variants of the same dis-ease, known as chronic actinic dermatitis, defined on the basis of the following criteria: 1) dermatitis of photo-exposed areas; 2) eczema-matched histological appearance (or with lymphoma-like changes); and 3) reduction of MED for UVB (mJ/c[m.

KEY WORDS: Actinic keratoses, Cryotherapy, Acnalen 0.

NORDIC BUSINESS REPORT-June 23, 2011--Swedish Meda applies for approval of actinic keratosis product in Europe(C)2011 M2 COMMUNICATIONS http://www.

Washington, Dec 1 (ANI): A new study has shown that the NSAID Celebrex may help prevent some non-melanoma skin cancers from developing in patients who have pre-cancerous actinic keratoses lesions and are at high risk for having the disease.

Diets that include oily fish and moderate wine consumption may reduce the risk of actinic keratosis, according to an Australian study.

MONTREAL -- Actinic keratoses are dynamic lesions and their expression varies over time, based on an 11-month study of the natural course of the lesions in people with extensive actinic damage.