actinism

[ClickPress, Wed May 08 2019] Actinic keratosis is prevalent as the initial clinical manifestation of a disease continuum in sun-damaged skin which may led to invasive squamous cell carcinoma.

The differential diagnosis of HA includes other photosensitive disorders that present with lesions on the skin after visible light exposure, such as HV, pinpoint PMLE, lichen nitidus, and actinic prurigo.

Differential diagnosis includes contact cheilitis, atopic cheilitis, actinic cheilitis, etc.

Abtahi-Naeini, "Topical colchicine gel versus diclofenac sodium gel for the treatment of actinic keratoses: a randomized, double-blind study," Advances in Medicine, vol.

A 59-year-old farmer on HC for ET was referred due to multiple, hyperkeratotic AK accumulating in chronically sunexposed skin areas: the hands, ears, almost the entire balding scalp, and large portions of the face, accompanied by severe actinic cheilitis.

This was diagnosed as actinic keratosis on histological examination.

KX2-391, also known as KX-01, is a first-in-class dual Src kinase and tubulin polymerization inhibitor in Phase III development as a topical medicinal product for the treatment of actinic keratosis.

Thus chronic sun exposure may have been overlooked as a risk factor for developing SCC in a patient with vitiligo.4 Other factors contributing to actinic damage in sun-exposed vitiligo skin may be - duration of disease and intensity of ultraviolet (UV) exposure.5 Our patient had received high and prolonged doses of UV light because of his occupation.

Healthcare company Perrigo Company plc (NYSE:PRGO)(TASE:PRGO) reported on Tuesday the receipt of tentative approval from the US Food and Drug Administration (FDA) for the generic version of Picato Gel (ingenol mebutate) 0.015% indicated for the topical treatment of actinic keratosis.

A combined formulation of calcipotriol and 5-fluorouracil (5FU) outperformed 5-FU alone in reducing the number of actinic keratoses (AKs), with a shorter treatment course and less inflammation than typically seen with 5-FU alone, researchers reported in a study.

Five clinical variants are recognized: disseminated superficial actinic porokeratosis and its non actinic variant, classic porokeratosis of Mibelli, linear porokeratosis, porokeratosis palmaris et plantaris disseminata and punctate porokeratosis [2].

Ultraviolet radiation damage is the main cause of premalignant actinic keratoses as well as basal-cell carcinomas and squamous-cell carcinomas.

People with atopic dermatitis do not appear to be at greater risk for actinic keratosis or basal cell and squamous cell cancer, according to a recent population-based, cross-sectional study.

FARMERS and outdoor workers are particularly vulnerable to a skin condition known as actinic keratosis, it was revealed yesterday.