Swift disease has been known as erythroedema, acrodynia
, pink disease, dermatopolyneuritis, and various other names.
When mercury levels in urine are >40 [micro]g/l, symptoms such as fever, tremors, mood swings, insomnia and acrodynia
(pink disease in children) may develop; at levels >60 [micro]g/l, additional respiratory symptoms may develop.
Consideration should be given to other possible etiologies, such as infection (for example, streptococcus, staphylococcus, Epstein-Barr virus, adenovirus, measles, Rocky Mountain spotted fever, or leptospirosis), drug reaction (for example, to antibiotics, anticonvulsants, or antifungals), autoimmune disease (such as systemic juvenile idiopathic arthritis or polyarteritis nodosa), or acrodynia
(for example, a mercury hypersensitivity reaction).
Mercury exposure is also associated with acrodynia
(painful extremities), a rare hypersensitivity reaction to mercury (9).
. Children may present with needle-like pain in their hands and feet, along with myriad other symptoms, including weight loss, night sweats, restlessness, withdrawal, depression, and personality change.
Public health officials drew the connection between mercury hazards and house paint in August 1989, when a 4-year-old Michigan boy developed acrodynia
, a rare form of childhood mercury poisoning.
The boy was diagnosed as having mercury poisoning, also called acrodynia
or pink disease.
Among children, prolonged exposure to inorganic mercury also might cause acrodynia
, irritability, anorexia, and poor muscle tone (4).
Many systemic diseases are associated with advanced alveolar bone loss that may lead to premature loss of teeth, such as hypophosphatesia, Papillon-Lefevre syndrome, histiocytosis X, agranulocytosis, leukocyte adherence deficiency, neutropenias, leukemias, diabetes mellitus, scleroderma, fibrous dysplasia, acrodynia
, and Chediak-Higashi syndrome [Armitage, 1999].
Photophobia has been reported in children with acrodynia
(Fagala & Wigg 1992; Warkany & Hubbard, 1953).
No family members exhibited erethism, gingivitis, tremor, or acrodynia
. On 29 July, the son had a blood mercury level of 16 [micro]g/L (laboratory reference range [less than or equal to] 13 [micro]g/L) and a 24-hr urine mercury level of 25 [micro]g/L.
. Children may present with needlelike pain in their hands and feet, along with myriad other symptoms, including weight loss, night sweats, restlessness, withdrawal, depression, and personality change.
Mercury exposure in the home may lead to acrodynia
* Dermatologic effects range from mild rashes and eczema to total body rash, or acrodynia
Children may experience acrodynia
, which is characterized by pink-colored palms and soles of the feet, excessive sweating, flushing, itching, joint pain, rashes, swelling, weakness, irritability, worry, and trouble sleeping (ATSDR 1999).