Whereas Polkowski et al (9) noted pancreatic
acinar cells in 14% of cases, Sarbia et al (10) found pancreatic
acinar cells in 61% of specimens.
Kubasik-Juraniec, "Changes in the morphology of the
acinar cells of the rat pancreas in the oedematous and necrotic types of experimental acute pancreatitis," Folia Morphologica, vol.
Asami et al., "Ligand-bound thyroid hormone receptor contributes to reprogramming of pancreatic
acinar cells into insulin-producing cells," Journal of Biological Chemistry, vol.
The cytoplasm of
acinar cells was filled with mitochondria, rough endoplasmic reticulum and Golgi complex at 49.5 cm CVRL (185th day).
In the normal state these enzymes are synthesized in pancreatic
acinar cells as inactive pro-enzymes (such as trypsinogen) and are maintained in this state until activated by enterokinase upon entry into the gut lumen.
1990, 1992) demonstrated that an alcohol diet or treatment of isolated lysosomes with FAEEs or cholesteryl esters caused lysosomal fragility and leakage of lysosomal enzymes into the
acinar cell cytosol.
Goodman et al., "Notch and Kras reprogram pancreatic
acinar cells to ductal intraepithelial neoplasia," Proceedings of the National Academy of Sciences of the United States of America, vol.
The effects of picroside II on cerulein-induced SAP rats were assessed based on the improvement of edema,
acinar cell necrosis, hemorrhages, and inflammation by preservation of the pancreatic architecture in comparison with the rats from the SAP group without picroside II treatment.
Chaudhary, "
Acinar cell carcinoma of the pancreas: a literature review and update," Indian Journal of Surgery, vol.
MAP has a short course, and the pancreatic structure and function couldbefully restored, while, inS AP, oncethe
acinar cells necrosis happened, the rupture of
acinar cell membrane could release a series of inflammatory factors, including TNF-[alpha] and IL-6, resulting in systemic inflammatory response syndrome; at the same time, the pancreatic structure and function would be damaged seriously.
Increases intraductal pressure, causing enzyme-rich interstitial fluid to accumulate, which causes fat necrosis and attracts immune cells that release cytokines, attacking acini and cause interstitial edema, which impairs blood flow and causes ischemia and
acinar cell injury [42].
(11) However, s-MRCP may be insensitive for detecting mild exocrine deficiency or small changes in exocrine function, as secretin affects only ductal cell secretion and does not stimulate
acinar cell secretion.
Franz tumor, solid and papillary epithelial neoplasm (SPEN), solid and papillary tumor, solid and cystic tumor, papillary-cystic tumor, papillary cystic epithelial neoplasm, and solid and cystic
acinar cell neoplasm are synonymous with SPT.
Acinar cell carcinoma of the pancreas (ACC) is a rare malignant epithelial tumor representing 1-2% of all exocrine pancreatic neoplasms [1].
Tang, "Amelioration of experimental acute pancreatitis with dachengqi decoction via regulation of necrosis-apoptosis switch in the pancreatic
acinar cell," PLoS ONE, vol.