The cuboidal or columnar epithelial cells have a markedly acidophil
cytoplasm and centrally located spherical nuclei when stained with H/E (Fig.
In addition, the liver biopsy confirmed the finding of DILI based upon the histological characteristics, notably the presence of eosinophils, rare acidophil
bodies, and focal mild portal inflammation.
Although liver is not the main target for this disease, histopathology findings include centrilobular necrosis, fatty alteration, hyperplasia of Kupffer cells, acidophil
bodies, and monocyte infiltration of portal tract.
Other rare variants thought to have more adverse prognosis include acidophil
stem cell adenoma (usually PRL immunostaining exceeds immunostaining for GH; also, this adenoma subtype contains scattered fibrous bodies on CAM5.2) (14(p101)) and Crooke cell ACTH adenomas, another type of adenoma in which use of CAM5.2 is helpful in subtyping.
symptoms examination) Left adrenalectomy Depressed XII.2005 (difuse and nodular mood, hyperplasia) anxiety I.2006 II.2006 Right adrenalectomy (difuse hyperplasia) III.2006 IV.2006 V.2006 Sleep disorder VII.2006 Pituitary Surgical resection Sleep fossa with (for the left adrenal disorder, homogenous remaining tissue) depressed content mood (10/6/15 mm) III.2007 Depressed mood, somatic complaints V.2008 Pituitary Transsphenoidal Anxiety, fossa with resection depression homogenous content VI.2009 Pituitary Transsphenoidal tumour resection (acidophil
(8/6 mm) pituitary adenoma) VII.2012 VII.2013 I.2014 normal INTRODUCERE
The basophil structures like nuclei are stained in color blue with hematoxilin, while eosin stains in pink acidophil
structures like collagen fibers.
Ghrelin is a peptide hormone that binds to growth hormone (GH) receptors and is primarily secreted by the acidophil
cells in the gastric fundic mucosa.