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Related to acetylcholinesterase inhibitor: anticholinesterase
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  • noun

Words related to anticholinesterase

a medicine that inhibits cholinesterase by combining with it and so has a cholinergic effect

References in periodicals archive ?
Screening for acetylcholinesterase inhibitors from Amaryllidaceae using silica gel thin-layer chromatography in combination with bioactivity staining.
Design, synthesis and evaluation og galanthamine derivates as acetylcholinesterase inhibitors.
Screening of non-alkaloidal natural compounds as acetylcholinesterase inhibitors.
This mechanism of action could potentially alleviate the undesirable side effects caused by other systemic compounds (for example, acetylcholinesterase inhibitors, or AChEIs), which are dose-limited by toxic side effects.
reported a randomized, controlled trial that found similar efficacy for another acetylcholinesterase inhibitor, donepezil.
Withdrawing acetylcholinesterase inhibitor drug treatments on the NHS for people diagnosed with mild AD is a grave error as clinical trials demonstrate that mild AD patients benefit significantly with measurable improvements in cognition and the ability to continue to participate in activities of daily living (ADL)," [4] states Dr Ian Howe, Medical Director of Shire Pharmaceuticals Limited.
Most excitingly, the cognition improvement was observed on top of the effect of acetylcholinesterase inhibitors the patients were already taking.
Shire plc (LSE: SHP, NASDAQ: SHPGY, TSX: SHQ) "Shire is encouraged that the new NICE appraisal consultation document for AD[1] acknowledges that the acetylcholinesterase inhibitor class of drugs are both clinically effective and cost-effective for the treatment of moderate AD and that they will remain available on the NHS," says John Freeman, Managing Director of Shire Pharmaceuticals' UK operation, which markets Reminyl(R) and Reminyl XL (galantamine)[2] in the UK.
The effect of two different doses of EHT 0202 (either 40 or 80 mg twice a day) as adjunctive therapy to one acetylcholinesterase inhibitor was evaluated in comparison to placebo.
The double-blind, randomized trial is the first to examine the effect of the Nmethyl-D-aspartate (NMDA) receptor antagonist memantine and the acetylcholinesterase inhibitor donepezil against donepezil monotherapy, said Dr.
Anticholinergic medications taken in addition to an acetylcholinesterase inhibitor in patients with Alzheimer's disease may have deleterious effects on acetylcholinesterase inhibitor therapy, suggested Ching-ju Lu and Dr.
Aricept(R) is an acetylcholinesterase inhibitor and is believed to work by inhibiting the breakdown of acetylcholine, thereby increasing available levels of this chemical in the brain.
In another case report, a 67-year-old woman who was taking paroxetine experienced confusion and exhibited aggressive behavior when she started taking the acetylcholinesterase inhibitor donepezil.
A randomized, placebo-controlled trial supported the validity of this approach: 359 patients with mild to moderate dementia diagnosed as probable mixed (Alzheimer's disease with cerebrovascular disease) or probable vascular dementia were given the acetylcholinesterase inhibitor galantamine; 178 received placebo.
Aricept, a selective acetylcholinesterase inhibitor for the treatment for Alzheimer's disease (AD), is a hugely significant product for Eisai, sales have shown impressive growth year-on-year since its launch in 1997.
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