HAT promote a cancer stem cell phenotype by inducing chromatin modifications (a), acting as a transcriptional coactivator (b) or
acetylating cancer stem cell transcription factors (c).
Some reports claim that aspirin is capable of
acetylating diverse cellular proteins such as human serum albumin [46], fibrinogen [47], hemoglobin [48], endothelial NOS [49], and tumor suppressor protein p53 [50] at the [N.sup.[epsilon]]-lysine residues, to regulate their functions [9].
3,5,4'-Tri-O-acetylresveratrol (TARES) synthesized by acetylating three hydroxyl groups of resveratrol (RES) is a prodrug of RES.
Accordingly, we protected the hydroxyl groups of RES from metabolism by acetylating them and synthesized 3,5,4'-tri-O-acetylresveratrol (TARES, Fig.
Acetylating starch has been reported to decrease its gelatinization temperature, increase its translucency, viscosity, freeze--thaw stability and reduce retrogradation [29].
Acetylating nonsteroidal anti-inflammatory drugs (NSAIDs), like aspirin, switches COX-2 from forming PGE(2) (promoting tumorigenesis) to 15-epi-LXA(4) (antitumorigenesis).
Protection of 1-butanol with different acetylating agents catalyzed by [H.sub.5]P[W.sub.10][V.sub.2][O.sub.40]
Table 2 describes protection of 1-butanol with different acetylating agents catalyzed by [H.sub.5]P[W.sub.10][V.sub.2][O.sub.40] under microwave.
The observed effect of reduction in paste viscosity at low degree of
acetylating is consistent with prevention of close association of chains due to steric hindrance effect of the acetyl groups.
Today, the preferred method of
acetylating wood is to use a limited amount of liquid acetic anhydride without a catalyst or cosolvent.
In vitro, SOHA induces differentiation and apoptosis in a variety of tumor cell lines by
acetylating histone proteins, thereby promoting normal DNA transcription.
SIRT1 improves mitochondrial function by activating adenosine monophosphateactivated protein kinase (AMPK) through
acetylating liver kinase B1 (LKB1) [58].
Isono, "Cloning and nucleotide sequencing of the genes rimI and rimJ which encode enzymes
acetylating ribosomal proteins S18 and S5 of Escherichia coli K12," Molecular & General Genetics, vol.
Evidence is presented here that human leukemia cells are capable of
acetylating 2-aminofluorene.