acetylate

HAT promote a cancer stem cell phenotype by inducing chromatin modifications (a), acting as a transcriptional coactivator (b) or acetylating cancer stem cell transcription factors (c).

Some reports claim that aspirin is capable of acetylating diverse cellular proteins such as human serum albumin [46], fibrinogen [47], hemoglobin [48], endothelial NOS [49], and tumor suppressor protein p53 [50] at the [N.sup.[epsilon]]-lysine residues, to regulate their functions [9].

Acetylating starch has been reported to decrease its gelatinization temperature, increase its translucency, viscosity, freeze--thaw stability and reduce retrogradation [29].

Acetylating nonsteroidal anti-inflammatory drugs (NSAIDs), like aspirin, switches COX-2 from forming PGE(2) (promoting tumorigenesis) to 15-epi-LXA(4) (antitumorigenesis).

The observed effect of reduction in paste viscosity at low degree of acetylating is consistent with prevention of close association of chains due to steric hindrance effect of the acetyl groups.

Today, the preferred method of acetylating wood is to use a limited amount of liquid acetic anhydride without a catalyst or cosolvent.

In vitro, SOHA induces differentiation and apoptosis in a variety of tumor cell lines by acetylating histone proteins, thereby promoting normal DNA transcription.

SIRT1 improves mitochondrial function by activating adenosine monophosphateactivated protein kinase (AMPK) through acetylating liver kinase B1 (LKB1) [58].

Isono, "Cloning and nucleotide sequencing of the genes rimI and rimJ which encode enzymes acetylating ribosomal proteins S18 and S5 of Escherichia coli K12," Molecular & General Genetics, vol.

Evidence is presented here that human leukemia cells are capable of acetylating 2-aminofluorene.