Average organic carbon contents (measured as a percentage [+ or -]2 SE; n = 5) of total shell mass measured in replicated subsamples of Mytilus edulis from the Lynher Estuary, Devon, UK, and Crassostrea gigas from the Avon River, Devon, UK, using a Carlo Erba elemental analyzer with acetanilide
at 925[degrees]C as a standard were 2.
In 1947, David Lester and Leon Greenberg discovered that paracetamol (acetaminophen) was a major, active metabolite of acetanilide
oxidation in phenylbutazone-associated hypoplastic anaemia.
at the time was already a widely-sold pain reliever, so he decided to add it.
The 1906 Pure Food and Drugs Act required some ingredients like alcohol, opium, chloral hydrate, and acetanilide
to be listed on the label or package.
Adams exposed how some headache powders, for instance, often sold by door-to-door salesmen, actually contained high levels of acetanilide
, a toxic and addictive painkiller that caused heart attacks and kidney disease.
In particular, the contribution of CYP1A and NAT2 enzymes to the metabolism of aniline-derived xenobiotics such as acetanilide
and phenacetin is well known (63).